Improving health in patients with COPD and sleep apnea through telehealth lifestyle changes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study tests a telehealth intervention aimed at improving the health of overweight and obese patients with Chronic Obstructive Pulmonary Disease (COPD) and Obstructive Sleep Apnea (OSA). It involves a randomized trial where participants will receive either a multi-component telehealth intervention or enhanced usual care. The intervention includes a self-directed lifestyle program and supervised pulmonary rehabilitation, with a follow-up recommendation for weight management medications after three months. The study will take place across five Department of Veterans Affairs medical centers.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* COPD: Defined by presence of airflow obstruction (FEV1/FVC \< 0.70) on post-bronchodilator spirometry
* ≥10 pack year history of tobacco use
* Self-reported clinician diagnosis of OSA (or presence of OSA on research HSAT)
* BMI ≥ 25 kg/m2
* Symptoms of dyspnea defined by MMRC score of ≥1

Exclusion Criteria:

* Self-report of weight change \>15 lbs. during prior 3 months
* Current active weight loss treatment, including: 1) research-based commercial weight loss programs (e.g., Weight Watchers, Jenny Craig, HMR, Omada, TOPS, MOVE!); 2) other weight loss or related behavioral health or wellness programs led by trained personnel (professional or lay) in the local community; 3) prescription weight loss medication within last 3 months; and scheduled bariatric surgery.
* Severe illness from any cause
* Diagnosis of bulimia or history of purging behavior
* Active enrollment in pulmonary rehabilitation
* Safety and/or adherence concerns due to severe physical or mental health issues or life expectancy \< 12 months. These include but may not be limited to: unstable cardiac arrhythmias, active or recent (within one month) myocardial infarction, active or recent (within one month) COPD exacerbation, angina not well-controlled with medication, significant musculoskeletal comorbidities or physical infirmities that preclude participation in an exercise program, and the need for supplemental oxygen ≥ 5 lpm at rest or with exertion.
* Pregnant, lactating, or planning to become pregnant during the study period
* Participation in other intervention studies.
* Prisoner
* Unable to complete surveys in English

Where it's running

• Boise VA Medical Center
  Boise, Idaho, United States Recruiting
• Jesse Brown VA Medical Center
  Chicago, Illinois, United States Recruiting
• Minneapolis VA Health Care System
  Minneapolis, Minnesota, United States Recruiting
• VA Puget Sound Health Care System
  Seattle, Washington, United States Recruiting
• Mann-Grandstaff VA Medical Center
  Spokane, Washington, United States Recruiting

Study contacts

• Study coordinator: Brianna Moss
• Email: brianna.moss@va.gov
• Phone: 206.277.4166

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Investigating the effects of sleep apnea and COPD on heart health

  This study is testing how having both sleep apnea and COPD affects heart health and whether a specific breathing treatment works better than oxygen therapy for improving heart outcomes in these patients.

  Recruiting Phase 2 University of California, San Diego · La Jolla, California · NCT05237505

• Multimodal Deep Learning to Predict Sleep Apnea Severity from SpO2 and Ballistocardiography

  Researchers are testing a smart-mattress-based method that uses SpO2 and ballistocardiography data to predict sleep apnea severity in adults undergoing overnight sleep study.

  Recruiting Fu Jen Catholic University · New Taipei City, New Taipei City · NCT07923825

• Nightly wearable monitoring with at-home submental electrical stimulation for sleep apnea

  This pilot test checks whether wearing a ring sensor at night and doing a 4-week at-home submental electrical stimulation is feasible for adults with obstructive sleep apnea and looks at changes in sleep metrics.

  Recruiting E-DA Hospital · Kaohsiung City · NCT07921329

• Functional capacity and muscle function in adults with obstructive sleep apnea

  This study tests how obstructive sleep apnea affects respiratory and peripheral muscle strength, endurance, and upper‑extremity function compared with healthy adults.

  Recruiting Karabuk University · Karabük · NCT07913139

• Transcutaneous Electrical Stimulation for Obstructive Sleep Apnea

  This study tests whether applying gentle electrical stimulation to the throat muscles at night can reduce sleep apnea severity in adults with obstructive sleep apnea.

  Recruiting Mansoura University · Al Mansurah, Dakahlia Governorate · NCT07891702

• Physical activity habits and sleep/ breathing in obstructive sleep apnea

  This study tests whether daily physical activity habits affect sleep quality and breathing measurements in people with obstructive sleep apnea who are on CPAP therapy.

  Recruiting Medipol University · Istanbul, Göztepe · NCT07889154

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.