Improving eye surface health before cataract surgery with Systane COMPLETE

Optimizing the Ocular Surface With Systane COMPLETE in Patients With Dry Eye Planning for Cataract Surgery

PHASE4 · National Taiwan University Hospital · NCT06763731

This study tests if using Systane COMPLETE can help people with dry eyes feel better before cataract surgery and improve their surgery results.

Quick facts

PhasePHASE4
Study typeInterventional
Enrollment150 (estimated)
Ages20 Years to 85 Years
SexAll
SponsorNational Taiwan University Hospital (other)
Locations1 site (Taipei, Taiwan)
Trial IDNCT06763731 on ClinicalTrials.gov

What this trial studies

This study evaluates the effects of regular use of Systane COMPLETE in patients with mixed dry eye who are preparing for cataract surgery. The objective is to determine how this treatment may optimize the ocular surface and improve predictions of residual astigmatism post-surgery. Participants aged 20-85 will be monitored for their ability to answer questionnaires and undergo pre-operative assessments. The study aims to enhance surgical outcomes by addressing dry eye symptoms prior to the procedure.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 20-85 with mixed dry eye who require cataract surgery.

Not a fit: Patients with significant ocular surface abnormalities or those currently using dry eye medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved surgical outcomes and visual acuity for patients undergoing cataract surgery.

How similar studies have performed: Other studies have shown positive outcomes with similar interventions in optimizing ocular surface health before surgery.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

The subjects aged 20-85 years, with normal cognitive function and capable of answering related questionnaires who require phacoemulsification and intraocular lens implantation under topical anaesthesia, are the eligible candidates.

Exclusion Criteria:

1. Unable to answer the questions in the dry eye survey.
2. Ocular trauma or ocular surgery in the planned surgical eye, active ocular infection, and obvious abnormalities in ocular surface or eyelid margins other than MGD cause decreased visual acuity other than cataracts.
3. Dry eye signs: Corneal Fluorescein Staining CFS (+) to exclude any corneal abnormalities or epithelial defect
4. Systemic drug use, including tetracycline derivatives, antihistamines, and isotretinoin.
5. Using dry eye medication at screening stage

Where this trial is running

Taipei, Taiwan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Ophthalmology, Dry eye, Cataract surgery

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.