Clinical trial Recruiting at 1 site Phase 4 Interventional Ages 20 to 85

Improving eye surface health before cataract surgery with Systane COMPLETE

Official title: Optimizing the Ocular Surface With Systane COMPLETE in Patients With Dry Eye Planning for Cataract Surgery

Run by National Taiwan University Hospital · NCT06763731 · Data updated 2026-11-12

This study tests if using Systane COMPLETE can help people with dry eyes feel better before cataract surgery and improve their surgery results.

Quick facts

PhasePhase 4
Study typeInterventional
Ages20 Years to 85 Years
SexAll
Enrollment150 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations1 site (Taipei, Taiwan)
StatusRecruiting
StartedMay 2, 2024
Main results expectedJanuary 14, 2027
Study endsDecember 31, 2027
Registry record updatedApril 23, 2026
Trial IDNCT06763731 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 20-85 with mixed dry eye who require cataract surgery.

Probably not a fit

Patients with significant ocular surface abnormalities or those currently using dry eye medications may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of regular use of Systane COMPLETE in patients with mixed dry eye who are preparing for cataract surgery. The objective is to determine how this treatment may optimize the ocular surface and improve predictions of residual astigmatism post-surgery. Participants aged 20-85 will be monitored for their ability to answer questionnaires and undergo pre-operative assessments. The study aims to enhance surgical outcomes by addressing dry eye symptoms prior to the procedure.

Why it matters

Potential benefit: If successful, this approach could lead to improved surgical outcomes and visual acuity for patients undergoing cataract surgery.

How similar studies have gone: Other studies have shown positive outcomes with similar interventions in optimizing ocular surface health before surgery.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

The subjects aged 20-85 years, with normal cognitive function and capable of answering related questionnaires who require phacoemulsification and intraocular lens implantation under topical anaesthesia, are the eligible candidates.

Exclusion Criteria:

1. Unable to answer the questions in the dry eye survey.
2. Ocular trauma or ocular surgery in the planned surgical eye, active ocular infection, and obvious abnormalities in ocular surface or eyelid margins other than MGD cause decreased visual acuity other than cataracts.
3. Dry eye signs: Corneal Fluorescein Staining CFS (+) to exclude any corneal abnormalities or epithelial defect
4. Systemic drug use, including tetracycline derivatives, antihistamines, and isotretinoin.
5. Using dry eye medication at screening stage

Where it's running

  • National Taiwan University Hospital
    Taipei, Taiwan, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.