Improving eye care in intensive care units

Effect of Evidence-Based Eye Care Protocol in Intensive Care Units

NA · TC Erciyes University · NCT05874453

This study tests if a new eye care routine can help prevent serious eye problems in patients on ventilators in intensive care units.

Quick facts

PhaseNA
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorTC Erciyes University (other)
Locations1 site (Kayseri)
Trial IDNCT05874453 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of an evidence-based eye care protocol on preventing ocular complications in patients in intensive care units. It involves a randomized controlled design where one eye of each patient will receive the intervention while the other serves as a control. The study aims to address the impaired eye protection mechanisms in mechanically ventilated patients, which can lead to serious complications like microbial keratitis and vision loss. A sample size will be determined based on G*Power analysis after reaching 40 patients.

Who should consider this trial

Good fit: Ideal candidates include patients who are newly intubated and connected to mechanical ventilation without prior eye conditions.

Not a fit: Patients with existing eye infections, chronic eye conditions, or those who have received certain topical therapies may not benefit from this study.

Why it matters

Potential benefit: If successful, this protocol could significantly reduce the incidence of ocular complications and improve visual outcomes for critically ill patients.

How similar studies have performed: While the specific approach may be novel, similar studies have indicated that structured eye care protocols can improve outcomes in critically ill patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients connected to mechanical ventilator,
* Newly intubated patients,
* Patients who have not been diagnosed with keratopathy and keratoconjunctivitis as of hospitalization,
* Patients who have not been diagnosed with burns and facial injuries,
* Patients without chronic lagophthalmos and eye trauma before ICU admission

Exclusion Criteria:

* Patients who have received topical drug therapy other than ocular lubrication
* Patients with muscle weakness as a result of cranial nerve VII (facial) nerve palsy
* Patients with chronic lagophthalmos and eye infections
* Those with rheumatological diseases
* Those with neurological/neuropathic disease that will affect eye closure

Where this trial is running

Kayseri

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Ocular Complications, Eye Protocol, eye protocol, ocular complications, intensive care, nursing care

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.