Improving energy balance in overweight individuals through exercise and cognitive training

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The RESILIENT project investigates how cognitive and social training can enhance leptin sensitivity in overweight individuals, including children. Participants will undergo an 8-week intervention that combines Intensive Health Behaviour Treatment with cognitive and social training, followed by a 12-week washout period. The study will assess leptin sensitivity through various methods, including measuring leptin levels in relation to caloric intake and analyzing leptin signaling in blood cells. Additionally, clinical, psychological, cognitive, and physiological evaluations will be conducted to determine the effectiveness of the interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* a condition of overweight or obesity
* Intelligence Quotient (IQ) ≥ 85

Exclusion Criteria:

* genetic or syndromic obesity;
* reduced mobility;
* systemic diseases;
* ongoing pharmacological treatment for chronic conditions.

Where it's running

• Ospedale Pediatrico Bambino Gesù
  Rome, Italy, Italy Recruiting
• Bambino Gesù Hospital and Research Institute,
  Rome, Rome, Italy Recruiting

Study contacts

• Study coordinator: Melania Manco
• Email: melania.manco@opbg.net
• Phone: +39 3317775547

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.