Improving early detection of periodontal disease through self-assessment and screening

Diagnostic Accuracy of Self-Reported Parameters, Oral and Systemic Biomarker Profile for the Detection of Periodontal Health and Disease

Observational Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University · NCT05513599

This study is testing a new way for people to spot early signs of gum disease by using simple questionnaires and self-checks to see if it helps identify the problem better.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
Ages18 Years and up
SexAll
SponsorShanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University Academic / other
Locations1 site (Shanghai, Shanghai)
Trial IDNCT05513599 on ClinicalTrials.gov

What this trial studies

This study focuses on enhancing the early detection of periodontal disease, which is often undiagnosed in the population. It evaluates the effectiveness of self-reported symptoms and simple non-clinical tests, such as questionnaires and gingival bleeding on brushing (GBoB), in identifying signs of periodontal health and disease. The approach aims to combine demographic information, self-assessment, and biochemical markers to create a reliable screening method. The validation of this diagnostic strategy will involve assessing its accuracy in a development group and confirming it in an independent population.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and above who can provide informed consent.

Not a fit: Patients who are edentulous, pregnant, or have received recent periodontal treatment or antibiotics may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to earlier diagnosis and treatment of periodontal disease, improving oral and overall health outcomes for patients.

How similar studies have performed: Other studies have shown promise in using self-assessment and biochemical markers for early detection of periodontal disease, indicating that this approach is both relevant and potentially effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aged 18 and above
* Ability and willingness to give written informed consent

Exclusion Criteria:

* Edentulous mouth
* Pregnant females
* Having received professional periodontal treatment (other than supragingival cleaning) within the previous 12 months
* Having received antibiotic medication within the previous 3 months
* Presence of bleeding disorders interfering with blood draw
* Presence of xerostomia interfering with saliva sampling
* Inability or unwillingness of individual to give written informed consent

Where this trial is running

Shanghai, Shanghai

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions PeriodontitisDiagnosisSelf-Assessment
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.