Improving diabetes management for older adults at risk of low blood sugar
Official title: Pragmatic Clinical Trial of Continuous Glucose Monitoring-based Interventions for Safe Insulin Use in High-Risk Older Adults With Type 2 Diabetes
Run by Kaiser Permanente · NCT06296485 · Data updated 2026-11-12
This study tests a new educational program using continuous glucose monitoring to help older adults with type 2 diabetes avoid dangerous low blood sugar levels.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 75 Years and up |
| Sex | All |
| Enrollment | 360 (estimated) |
| Sponsor | Kaiser Permanente Academic / other |
| Locations | 6 sites (Fremont, California and 5 other locations) |
| Status | Recruiting |
| Started | May 1, 2024 |
| Main results expected | September 30, 2027 |
| Study ends | January 31, 2028 |
| Registry record updated | August 4, 2026 |
| Trial ID | NCT06296485 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are older adults aged 75 and above who have type 2 diabetes and are currently using insulin.
✕Probably not a fit
Patients who are on renal dialysis, have dementia, or are using insulin pumps may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to enhance diabetes care for older adults aged 75 and above who have type 2 diabetes and are at risk for severe hypoglycemia. It evaluates a novel educational program that utilizes continuous glucose monitoring (CGM) to support safe insulin prescribing. Participants will be randomly assigned to either a group-based education intervention with CGM or to usual care without CGM. The study will measure the incidence of clinically significant hypoglycemia and assess patient-reported outcomes related to diabetes distress and self-efficacy.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the risk of severe hypoglycemia in older adults with type 2 diabetes, improving their overall health and quality of life.
How similar studies have gone: While there have been studies on diabetes management in older adults, this specific approach using CGM for hypoglycemia prevention is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 75 years and older * Diagnosis of Type 2 Diabetes * Current treatment with insulin * Increased hypoglycemia risk (prior year hypoglycemia by self-report or utilization) * Able to communicate in English * Able to access email and the Internet Exclusion Criteria: * On renal dialysis * Dementia * Pacemaker or Automatic Implantable Cardioverter Defibrillator * Using insulin pump * Severe Mental Illness * Severe Visual Impairment * In Hospice * Current or recent CGM use
Where it's running
-
Kaiser Permanente Sacramento
Sacramento, California, United States Recruiting -
Kaiser Permanente Fremont
Fremont, California, United States Completed -
Kaiser Permanente San Jose
San Jose, California, United States Completed -
Kaiser Permanente San Leandro
San Leandro, California, United States Completed -
Kaiser Permanente Santa Clara
Santa Clara, California, United States Completed -
Kaiser Permanente - Union City
Union City, California, United States Completed
Study contacts
- Principal investigator: Richard W Grant, MD MPH — Kaiser Permanente Northern California - Division of Research
- Study coordinator: Carolina Gonzalez
- Email: Susana.C.Gonzalez@kp.org
- Phone: 866-206-2969
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.