Improving colonoscopy follow-up for patients with high risk colon polyps
Multilevel Health System Intervention to Increase Guideline-Concordant Surveillance Colonoscopy for High Risk Colon Polyps
NA · Jonsson Comprehensive Cancer Center · NCT06376565
This study is testing whether better reminders and support for scheduling can help patients with high risk colon polyps get their follow-up colonoscopies done on time to lower their chances of developing colorectal cancer.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 1680 (estimated) |
| Ages | 21 Years and up |
| Sex | All |
| Sponsor | Jonsson Comprehensive Cancer Center (other) |
| Locations | 1 site (Los Angeles, California) |
| Trial ID | NCT06376565 on ClinicalTrials.gov |
What this trial studies
This clinical trial tests a multilevel intervention aimed at enhancing colonoscopy surveillance for patients diagnosed with high risk colon polyps. The study involves interviews with participants and randomization of primary care clinics into two groups: one receiving enhanced reminders and scheduling support for colonoscopy, and the other continuing with standard care practices. The primary goal is to increase the rate of completed surveillance colonoscopies within 3.5 years of high risk neoplasia diagnosis, thereby reducing the risk of colorectal cancer. The intervention includes automated health record updates, patient reminders, and proactive scheduling calls.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 45 to 75 who have been diagnosed with high risk neoplasia within the past five years.
Not a fit: Patients with a personal history of colorectal carcinoma, inflammatory bowel disease, or polyposis syndrome may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the timely detection and prevention of colorectal cancer in high risk patients.
How similar studies have performed: Other studies have shown success with similar multilevel interventions aimed at improving cancer screening adherence, suggesting a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * AIM 1 PATIENTS: Patients between age 45 and 75 with a HRN diagnosis in the past 5 years * AIM 1 PATIENTS: 12 patients who did and 12 patients who did not have surveillance colonoscopy * AIM 1 PROVIDERS: Primary care providers (PCPs) and gastroenterologists (GIs) * AIM 1 ADMINISTRATORS: Administrators who are involved in care processes related to CRC screening, HRN surveillance, and/or colonoscopy scheduling * AIM 2: Patients age 45 to 75 diagnosed with a HRN during the pre-specified two-year HRN diagnosis period Exclusion Criteria: * AIM 2: Individuals with a personal history of colorectal carcinoma (CRC), inflammatory bowel disease (Crohn's, ulcerative colitis), or polyposis syndrome * AIM 2: HRN cases not confirmed by chart review (human-in-the-loop)
Where this trial is running
Los Angeles, California
- UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California, United States (RECRUITING)
Study contacts
- Principal investigator: Folasade P May — UCLA / Jonsson Comprehensive Cancer Center
- Study coordinator: Jenna Alarcon
- Email: JCAlarcon@mednet.ucla.edu
- Phone: 310-794-6197
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Colorectal Carcinoma