Improving cognitive tasks after stroke using computer games
Transferring Speed of Processing Gains to Everyday Cognitive Tasks After Stroke
NA · University of Alabama at Birmingham · NCT05162781
This study tests two different ways to help adults with mild to moderate cognitive issues after a stroke by using computer games to see which method works better for improving their thinking skills.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 82 (estimated) |
| Ages | 40 Years and up |
| Sex | All |
| Sponsor | University of Alabama at Birmingham (other) |
| Locations | 1 site (Birmingham, Alabama) |
| Trial ID | NCT05162781 on ClinicalTrials.gov |
What this trial studies
This study compares two cognitive rehabilitation approaches for adults with mild to moderate cognitive impairment following a stroke. Both methods utilize a web-based game designed to enhance cognitive processing speed. One approach, Constraint-Induced Cognitive Therapy (CICT), includes in-lab training on everyday activities and strategies to apply cognitive improvements in daily life. The other approach, Brain Fitness-Health Education Lifestyle Program (BF-HELP), focuses on relaxation, nutrition, and sleep, along with promoting lifestyle changes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 40 and older who have experienced a stroke more than a year ago and exhibit mild to moderate cognitive impairment.
Not a fit: Patients with cognitive impairment due to developmental disorders or those unable to participate in the required assessments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly enhance cognitive functioning and daily living skills for stroke survivors.
How similar studies have performed: Previous studies have shown promise in cognitive rehabilitation approaches similar to those being tested, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Primary Inclusion Criteria: * stroke \> 1 year previously * mild-to-moderate general cognitive impairment as determined by a Montreal Cognitive Assessment (MOCA) score between 10-26 * some impairment in performance of daily activities; this will be determined by a score of 3 or below on the Cognitive Task Activity Log (CTAL) Additional Inclusion Criteria: * 40 years or older; no upper limit if medically stable * sufficiently fit, from both a physical and mental health perspective, to take part in study * adequate sight and hearing to complete UFOV test * adequate thinking skills, e.g., ability to follow directions, retain information, to complete UFOV and CTAL, as marked by judgement of the screener that the candidate is able to adequately complete the UFOV and CTAL * reside in the community (as opposed to a hospital or skilled nursing facility) * able to travel to laboratory on multiple occasions * caregiver available Exclusion Criteria: * cognitive impairment due to a developmental disability, psychiatric disorder, or substance abuse or due to another type of brain injury, such a traumatic brain injury, or a progressive brain disease, such as Alzheimer's Dementia
Where this trial is running
Birmingham, Alabama
- University of Alabama at Birmingham — Birmingham, Alabama, United States (RECRUITING)
Study contacts
- Principal investigator: Gitendra Uswatte, PhD — University of Alabama at Birmingham
- Study coordinator: Staci McKay, BS
- Email: stacemc@uab.edu
- Phone: 205-934-9768
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Stroke, Cognitive Dysfunction, stroke, cognitive dysfunction, cognitive processing speed, IADL