Improving care for patients with multiple chronic conditions in primary care

Effectiveness of an Adaptive, Complex Intervention to Enhance Care for Patients With Complex Multimorbidity in General Practice - a Pragmatic Cluster Randomized Controlled Trial

Not applicable Interventional University of Copenhagen · NCT05676541

This study tests a new way to improve care for people with multiple chronic conditions by providing more personalized support in their primary care visits to see if it helps them feel better and use healthcare services less.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50000 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Copenhagen Academic / other
Locations1 site (Copenhagen)
Trial IDNCT05676541 on ClinicalTrials.gov

What this trial studies

This study evaluates a complex intervention designed to enhance care for patients with multimorbidity in general practice settings. It focuses on providing integrated, patient-centered care to individuals with multiple chronic conditions, addressing the challenges they face, such as high treatment burden and fragmented care. The intervention includes an extended overview consultation and additional supportive elements to streamline care and improve patient outcomes. The study aims to assess the effectiveness of this approach in improving quality of life and reducing healthcare utilization among affected patients.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older with two or more chronic conditions and a history of secondary care contact.

Not a fit: Patients with only one chronic condition or those not actively engaged in secondary care may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the quality of life and care coordination for patients with multiple chronic conditions.

How similar studies have performed: Other studies have shown success in enhancing care for patients with multimorbidity through integrated approaches, suggesting potential for positive outcomes in this study.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Adult (18 years or older) patients listed at participating GPs living in their own home with

* Two or more chronic conditions from two of ten diagnosis groups OR who were identified by the GP with complex multimorbidity (see box 1)
* At least one contact with secondary care in 2022 or 2023.
* Prescribed at least five prescription drugs

Where this trial is running

Copenhagen

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Multimorbidity
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.