Improving care for patients with Graves' disease

The Impact of Person Centred Care (PCC) on Mental Outcome and Work Ability in Graves' Disease - the GRAves CarE (GRACE) PCC Project

NA · Vastra Gotaland Region · NCT06309316

This study is testing if a new approach to care that involves patients more actively can help adults with Graves' disease feel less mentally tired and improve their overall health.

Quick facts

PhaseNA
Study typeInterventional
Enrollment220 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorVastra Gotaland Region (other gov)
Locations1 site (Gothenburg)
Trial IDNCT06309316 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of person-centred care (PCC) on patients suffering from mental fatigue after experiencing Graves' disease, a common form of hyperthyroidism. It aims to engage patients as active partners in their care, promoting positive coping strategies and enhancing self-efficacy. The hypothesis is that PCC will lead to improvements in mental fatigue, reduced sick leave, and lower recurrence rates of Graves' disease. The study will involve patients aged 18-65 who are experiencing their first episode of Graves' disease.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18-65 who have been diagnosed with their first episode of Graves' disease.

Not a fit: Patients with moderate to severe Graves' eye disease or those unable to comply with the study protocol may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve the quality of life for patients by reducing mental fatigue and enhancing their overall well-being.

How similar studies have performed: While the concept of person-centred care is gaining traction, this specific application in Graves' disease is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 18-65 years
* First time Graves' diseases with elevated FT4 and/or FT3 and positive TSH receptor antibody (TRAb)

Exclusion Criteria:

* Patients that cannot attend to the protocol
* Patients with moderate-severe/ severe Graves' eye disease

Where this trial is running

Gothenburg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Graves Disease, Person Centred Care, Mental fatigue, cost-effectiveness, self-efficacy, eHealth

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.