Improving care for childhood cancer survivors

BRidging Information Divides and Gaps to Ensure Survivorship: the BRIDGES Randomized Controlled Trial of a Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship

This study is testing a new way to help childhood cancer survivors get better follow-up care by using telehealth, tailored education, and improved communication between their doctors.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 240 (estimated)
• Ages: 2 Years and up
• Sex: All
• Sponsor: Georgetown University (other)
• Drugs / interventions: chemotherapy, radiation
• Locations: 4 sites (Long Beach, California and 3 other locations)
• Trial ID: NCT05448560 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates a multi-level intervention aimed at enhancing adherence to survivorship care among childhood cancer survivors. The approach includes patient education through telehealth, tailored educational programs in electronic health records, structured communication between cancer centers and primary care clinics, and in-person visits for survivorship care. By addressing barriers such as knowledge gaps and logistical challenges, the study seeks to improve patient outcomes and ensure that survivors receive necessary follow-up care. The trial will enroll 240 participants who are 2 to 4 years post-therapy to evaluate the effectiveness of this innovative care model.

Who should consider this trial

Good fit: Ideal candidates for this study are childhood cancer survivors who were diagnosed before age 21, completed their cancer treatment 2 to 4 years ago, and have not previously attended a specialty survivorship clinic.

Not a fit: Patients with active medical problems that prevent them from receiving survivorship care with a primary care provider will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the health outcomes and quality of life for childhood cancer survivors by ensuring they receive appropriate follow-up care.

How similar studies have performed: Other studies have shown success with similar multi-level interventions in improving care adherence, making this approach promising yet still innovative.

Eligibility criteria

Inclusion Criteria:

1. Diagnosed with any cancer at age \<21 years
2. Treated with chemotherapy and/or radiation
3. 2.0-4.0 years status post-completion of all cancer-related therapy
4. Cancer-free with a life expectancy of ≥2 years
5. English- or Spanish-speaking (also applies to parent/guardian if patient age \<18 years)
6. No previous attendance at a specialty survivorship clinic
7. Followed at one of the 4 participating sites: Hackensack, University of North Carolina- Chapel Hill (UNC), University of Colorado Denver (CU), Miller's Children's and Women's Hospital Long Beach (MCWH)

Exclusion Criteria:

* Active medical problems severe enough to not be eligible for receiving survivorship care with primary care provider at the time of recruitment

Where this trial is running

Long Beach, California and 3 other locations

• MemorialCare Miller Children's & Women's Hospital Long Beach — Long Beach, California, United States (RECRUITING)
• Children's Hospital Colorado — Denver, Colorado, United States (RECRUITING)
• Hackensack University Medical Center — Hackensack, New Jersey, United States (RECRUITING)
• University of North Carolina Children's Hospital — Chapel Hill, North Carolina, United States (RECRUITING)

Study contacts

• Principal investigator: Nina Kadan-Lottick, MD, MSPH — Georgetown Lombardi Comprehensive Cancer Center
• Study coordinator: Nina Kadan-Lottick, MD, MSPH

Conditions: Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice, Adherence, Patient, childhood cancer survivors, survivorship care, randomized controlled trial