Impedance-based Sensing During DVT Care

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study collects multi-frequency impedance plethysmography data from 40 participants (20 healthy volunteers and 20 DVT patients undergoing thrombolytic therapy) using a ThrombUS+ prototype and a reference IPG device. The goal is to develop signal processing, data analysis, and machine learning algorithms for DVT detection and assessment. The study will review how IPG data aligns with angiography, ultrasound, and venous occlusion plethysmography, and explore whether multi-frequency measurements improve detection. Interventions to modulate venous blood volume include venous occlusion, breathing, and leg movement. Secondary work includes exploring simulations of DVT to compare performance of different approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria for Patients group:

* Age: 18 or older;
* DVT detected on other lower limb;
* Suitable for CDT treatment;
* Ability to give informed consent;
* Volunteering for the study.

Exclusion Criteria for Patients group:

* Age under 18 years;
* Inability to give informed consent;
* Denial;
* Too injured skin in the measurement area

Inclusion Criteria for Healthy volunteers group:

* Age: 18 or older;
* Ability to give informed consent;
* Volunteering for the study

Exclusion Criteria for Healthy volunteers group:

* Diagnosed DVT in lower limbs;
* Age under 18 years;
* Inability to give informed consent;
* Denial;
* Too injured skin in the measurement area.

Where it's running

• Tampere University Hospital
  Tampere, Finland Recruiting
• Tampere University
  Tampere, Finland Completed

Study contacts

• Study coordinator: Vehkaoja
• Email: antti.vehkaoja@tuni.fi
• Phone: +358407393181

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.