Progressive gait training for people after a first lower‑leg deep vein thrombosis
Official title: Progressive Gait Training After First-time Deep Venous Thrombosis: Clinical Effectiveness and Involved Mecanisms (The DVT-Cph RCT)
Run by Hvidovre University Hospital · NCT06909240 · Data updated 2026-11-12
This will test if adding progressive walking (gait) training to standard care improves quality of life for adults after a first lower‑extremity DVT.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 152 (estimated) |
| Sponsor | Hvidovre University Hospital Academic / other |
| Locations | 1 site (Hvidovre, Capital Region) |
| Status | Recruiting |
| Started | November 15, 2025 |
| Main results expected | April 1, 2028 |
| Study ends | February 1, 2030 |
| Registry record updated | January 23, 2026 |
| Trial ID | NCT06909240 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) hospitalized with a first‑time lower‑extremity DVT who have a Danish social security number, can cooperate cognitively and physically, and understand Danish.
✕Probably not a fit
Patients with terminal illness, those who cannot understand Danish, or those without a Danish social security number are not eligible and therefore would not be expected to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized controlled trial will enroll adults hospitalized with a first lower‑extremity DVT and randomly assign them to progressive gait training plus standard care or to standard care alone. The primary clinical aim is to test whether the added progressive walking program improves quality of life, while mechanistic aims track disease progression, post‑thrombotic syndrome, and severity of venous thromboembolism. A preceding feasibility trial will examine intervention practicality and patient experiences, and participants may also join a parallel cohort studying inflammatory, immunological, and ageing biomarkers. The trial is led by Hvidovre University Hospital in the Capital Region of Denmark.
Why it matters
Potential benefit: If successful, the intervention could improve patient quality of life and reduce long‑term complications such as post‑thrombotic syndrome.
How similar studies have gone: Exercise and rehabilitation interventions after DVT have limited prior data with some small studies suggesting symptomatic or mobility benefits, but progressive gait training for first‑time DVT is relatively novel and not yet proven.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18 years or above * First time lower extremity DVT * Hospitalized at the Emergency Department * Can cooperate cognitively and physically (patient reported) Exclusion Criteria: * Patients without a Danish social security number * Terminal patients * Patients who do not understand or speak Danish
Where it's running
-
Hvidovre University Hospital
Hvidovre, Capital Region, Denmark Recruiting
Study contacts
- Principal investigator: Helle Juul-Larsen, Ph.D. — Hvidovre University Hospital
- Study coordinator: Mette Merete Pedersen, Ph.D.
- Email: mette.merete.pedersen@regionh.dk
- Phone: +4538623350
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.