Impact of Vitamin D on Pregnancy and Prematurity Outcomes
Effects of Vitamin D on Health Promotion During Pregnancy and Its Impact on Prematurity-Related Outcome Indicators in the Alentejo Region
This study is trying to see if the amount of vitamin D in pregnant women affects the chances of premature birth and how it impacts both mothers and their babies.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1000 (estimated) |
| Ages | 16 Years and up |
| Sex | Female |
| Sponsor | University of Évora Academic / other |
| Locations | 3 sites (Beja and 2 other locations) |
| Trial ID | NCT06292195 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between maternal vitamin D levels and prematurity outcomes in pregnant women from the Alentejo region of Portugal. It aims to recruit at least 1000 participants from various healthcare centers, collecting data on vitamin D levels during pregnancy and their effects on maternal and child health. The study will also explore genetic factors that may influence vitamin D metabolism and associated risks of adverse outcomes related to prematurity. Blood and saliva samples will be collected at two key points: during the first prenatal visit and postpartum.
Who should consider this trial
Good fit: Ideal candidates are pregnant women aged 16 years or older living in the Alentejo region who can provide informed consent.
Not a fit: Patients who do not speak Portuguese may not benefit from this study due to language barriers.
Why it matters
Potential benefit: If successful, this study could lead to improved maternal and child health outcomes by addressing vitamin D deficiency and reducing preterm births.
How similar studies have performed: While similar studies have shown associations between vitamin D levels and pregnancy outcomes, this specific investigation in the Portuguese population is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women's living in the Alentejo region aged 16 years or older, who after disclosure and clarification of doubts, agree to participate in the study with signed informed consent. Exclusion Criteria: * Language barrier (lack of basic understanding of Portuguese).
Where this trial is running
Beja and 2 other locations
- Unidade Local de Saúde do Baixo Alentejo — Beja, Portugal (Recruiting)
- Unidade Local de Saúde do Norte Alentejano — Portalegre, Portugal (Recruiting)
- Unidade Local de Saúde do Alentejo Central - Hospital Espirito Santo de Évora — Évora, Portugal (Recruiting)
Study contacts
- Principal investigator: Maria OP Barbosa, MSc; PhD student — University of Évora
- Study coordinator: Maria OP Barbosa, MSc; PhD student
- Email: d52901@alunos.uevora.pt
- Phone: 00351966056178
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.