Impact of resistance training with blood flow restriction on atherosclerosis patients
Effect of Physiological Ischemic Training on Patients With Atherosclerosis
This study tests if doing resistance training with blood flow restriction can help people in the early stages of atherosclerosis improve their heart health and prevent the condition from getting worse.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | Nanjing First Hospital, Nanjing Medical University Academic / other |
| Locations | 1 site (Nanjing, Jiangsu) |
| Trial ID | NCT05091762 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of resistance training combined with blood flow restriction on patients in the early stages of atherosclerosis. The intervention aims to determine if this exercise approach can help prevent the progression of atherosclerosis in individuals with specific lipid profiles. Participants will engage in a structured exercise regimen while monitoring their cardiovascular health. The study focuses on patients who have not engaged in regular exercise recently and meet specific health criteria.
Who should consider this trial
Good fit: Ideal candidates include individuals with elevated LDL cholesterol levels who do not have serious cardiovascular or musculoskeletal diseases and have not exercised regularly in the past six months.
Not a fit: Patients with serious heart or vascular diseases, pregnant women, or those with disabilities may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a novel method for preventing the progression of atherosclerosis in at-risk patients.
How similar studies have performed: While there is emerging interest in blood flow restriction training, this specific approach in atherosclerosis patients is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. LDL \> 3.11mmol/l and less than 5.63mmol/l; 2. No serious heart, blood vessel and other related diseases; 3. There were no skeletal and muscular diseases affecting sports training; 4. No regular exercise in the past half year (no more than 2 times a week, no more than 30 minutes each time); 5. Smoking less than 1 pack / year, no history of drinking. Exclusion Criteria: 1. Haven't other serious heart and vascular diseases other than hyperlipidemia and / or bones and muscles that affect sports training Diseases; 2. Pregnant women and people with disabilities; 3. Other circumstances determined by the researcher not suitable for the study.
Where this trial is running
Nanjing, Jiangsu
- Nanjing First Hospital — Nanjing, Jiangsu, China (Recruiting)
Study contacts
- Study coordinator: Aicui Lin, PhD
- Email: linaicui@126.com
- Phone: +8615305179718
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.