Impact of recreational nitrous oxide on young people's neurological health

A Retrospective Study of Neurological Impairment in a Young Population Exposed to Recreational Nitrous Oxide

Observational Centre Hospitalier Universitaire de Nīmes · NCT05469321

This study looks at how using recreational nitrous oxide affects the brain health of young people to see if it causes any neurological problems.

Quick facts

Study typeObservational
Enrollment20 (estimated)
Ages15 Years and up
SexAll
SponsorCentre Hospitalier Universitaire de Nīmes Academic / other
Locations1 site (Nîmes)
Trial IDNCT05469321 on ClinicalTrials.gov

What this trial studies

This observational study investigates the neurological impairments in young individuals who have used recreational nitrous oxide (N2O). It focuses on the potential neuropsychiatric complications arising from N2O consumption, including neuropathy and cognitive disorders. The study aims to document the acute or sub-acute neurological symptoms presented by patients at the CHU of Nîmes after N2O exposure, analyzing the effects of vitamin B12 deficiency and direct toxicity of the gas. By observing these cases, the study seeks to enhance understanding of the risks associated with recreational N2O use.

Who should consider this trial

Good fit: Ideal candidates are young individuals presenting with acute or sub-acute neurological symptoms after nitrous oxide consumption.

Not a fit: Patients who have not used nitrous oxide or do not exhibit neurological symptoms will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to better awareness and management of neurological risks associated with nitrous oxide use in young populations.

How similar studies have performed: While there is limited research specifically on recreational nitrous oxide use, studies on its effects in clinical settings have indicated potential neurological risks, suggesting this area warrants further investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
patients presenting to the CHU of Nîmes with an acute or sub-acute neurological picture after having consumed N2O

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Where this trial is running

Nîmes

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Neuropathy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.