Impact of physical activity on surgery outcomes
Official title: Perioperative Impact After Non-cardiac Surgery of Physical Activity on Short- and Long-term Morbidity and Mortality
Run by Karolinska Institutet · NCT06678360 · Data updated 2026-11-12
This study is trying to see if being more physically active before surgery can help adults avoid complications and live longer after having non-heart-related surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 180000 (estimated) |
| Sponsor | Karolinska Institutet Academic / other |
| Locations | 1 site (Stockholm) |
| Status | Recruiting |
| Started | November 1, 2024 |
| Main results expected | August 31, 2025 |
| Study ends | December 1, 2025 |
| Registry record updated | June 6, 2025 |
| Trial ID | NCT06678360 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adult patients aged 18 and older who are scheduled for elective non-cardiac surgery.
✕Probably not a fit
Patients undergoing emergency surgeries, transplant procedures, or those under 18 years old may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational cohort study investigates the relationship between self-reported physical activity levels and the risk of complications and mortality in adult patients undergoing elective non-cardiac surgery. By collecting data on various factors such as age, sex, body mass index, and co-morbid conditions, the study aims to determine if higher Metabolic Equivalent of Task (MET) scores correlate with lower perioperative morbidity and mortality. The analysis will utilize multivariable methods to assess the impact of physical activity on surgical outcomes, providing valuable insights into modifiable risk factors in the perioperative setting.
Why it matters
Potential benefit: If successful, this study could help identify physical activity as a key factor in reducing surgical complications and improving patient survival rates.
How similar studies have gone: Previous studies have indicated a potential link between physical activity and improved surgical outcomes, suggesting that this approach may yield meaningful insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Adult patients (equal to or over 18 years) undergoing elective non-cardiac surgery at the two study sites, Karolinska University Hospital Solna and Karolinska University Hospital Huddinge Exclusion Criteria: Patients under the age of 18, transplant, day surgery, acute surgery, anesthesia monitoring, brachy therapy and gamma knife interventions. In case of multiple surgeries, only the first will be included.
Where it's running
-
Karolinska Institutet
Stockholm, Sweden Recruiting
Study contacts
- Principal investigator: Max Bell, MD, PhD — Karolinska Institutet
- Study coordinator: Max Bell, MD, PhD
- Email: max.bell@regionstockholm.se
- Phone: +46708278533
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.