Impact of Parenthood on Health in People with Cystic Fibrosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the health effects of parenthood on individuals with cystic fibrosis (CF) in the context of modern CFTR modulator therapies. It will follow 146 new parents of children under 5 years old across 18 CF centers in the US, assessing both physical and mental health outcomes over a period of up to 5 years. The study will investigate how factors such as depression and parental responsibilities influence lung function, measured by percent predicted forced expiratory volume in one second (ppFEV1). Additionally, qualitative interviews will be conducted to gather insights on the psychosocial impacts of parenthood and identify potential areas for intervention.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosed with cystic fibrosis via sweat test or genotype analysis
* Became a first-time parent (including foster parent, step parent, adoptive parent, or legal guardian) to a child under 5 years of age within the last 180 days

Exclusion Criteria:

* Undergone a lung transplant
* Does not speak/read English or Spanish

Where it's running

• University of Alabama-Birmingham
  Birmingham, Alabama, United States Recruiting
• National Jewish Health
  Denver, Colorado, United States Recruiting
• Northwestern University
  Evanston, Illinois, United States Recruiting
• Indiana University
  Indianapolis, Indiana, United States Recruiting
• University of Kansas Medical Center
  Kansas City, Kansas, United States Recruiting
• Johns Hopkins University
  Baltimore, Maryland, United States Recruiting

Study contacts

• Principal investigator: Traci M Kazmerski, MD — Faculty
• Study coordinator: Olivia M Stransky, MPH
• Email: stranskyom@upmc.edu
• Phone: 412-419-7984

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.