Clinical trial Recruiting at 1 site Interventional Ages 20 to 50

Impact of neuromuscular control with and without electrical stimulation for multidirectional shoulder instability

Official title: Impact of Neuromuscular Control With and Without Electrical Stimulation and Long-term Effect of Kinetic Chain Exercises in Multidirectional Shoulder Instability Patients

Run by National Taiwan University Hospital · NCT07611006 · Data updated 2026-11-12

This study tests whether neuromuscular training with or without electrical stimulation can improve shoulder control in adults with multidirectional shoulder instability linked to hypermobility conditions.

Quick facts

Study typeInterventional
Ages20 Years to 50 Years
SexAll
Enrollment60 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedNovember 9, 2025
Main results expectedJune 15, 2026
Study endsJuly 30, 2026
Registry record updatedMay 28, 2026
Trial IDNCT07611006 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 20–50 with generalized joint hypermobility (Beighton ≥4/9), evidence of shoulder laxity, chronic shoulder pain, and functional instability not caused by trauma.

Probably not a fit

Individuals without persistent instability or with non-hypermobile shoulder conditions may not experience benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial investigates people aged 20–50 with multidirectional shoulder instability and hypermobility disorders to see how neuromuscular training, with or without electrical stimulation, affects shoulder movement and muscle activity. Participants undergo interventions that combine neuromuscular electrical stimulation and neuromuscular control training to assess changes in humeral head translation and joint kinetics. The study aims to clarify how these approaches influence shoulder stability during movement and daily activity. It is conducted at a physical therapy program affiliated with National Taiwan University Hospital and local academic sites.

Why it matters

Potential benefit: If successful, participants may experience improved shoulder stability and reduced pain during daily activities and sports.

How similar studies have gone: Earlier research in musculoskeletal hypermobility and neuromuscular training has shown improvements in joint stability, though specific data for electrical stimulation in MDI with HSD/hEDS are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age: Between 20 and 50 years old.

Patients with Multidirectional Shoulder Instability Must Meet the Following Conditions:

(A) Generalized Joint Hypermobility: Beighton score ≥ 4/9. (B) Shoulder Laxity Verified in at Least Two Directions During Clinical Examination (must meet A and B, or A and C): Inferior: Presence of a sulcus sign under the acromion or a positive Gagey hyperabduction test.

Anterior: Positive anterior load and shift test or active shoulder external rotation \> 85 degrees or passive shoulder external rotation \> 90 degrees.

Posterior: Positive posterior load and shift test or positive posterior jerk test.

(C) Shoulder Pain for at Least Three Months Before the Start of the Study. (D) Signs of Shoulder Instability in Daily Life Without a Traumatic Cause. (E) Ability to Raise the Arm Above 120 Degrees Without Experiencing Subluxation or Dislocation of the Shoulder.

Exclusion Criteria:

* Shoulder pain caused by trauma. History of shoulder fractures or dislocations. Cervical radiculopathy. Degenerative joint disease of the shoulder. Previous shoulder surgery. Frozen shoulder. Pain score greater than 5 during experimental movements. Redness, swelling, or open wounds on the skin within the experimental area. Sensory abnormalities. Cognitive impairment.

Where it's running

  • School and graduate institution of physical therapy
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.