Clinical trial Recruiting at 1 site Observational

Impact of nerve monitoring on voice quality after thyroid surgery

Official title: Intraoperative Neuromuscular Monitoring and Its Impact on Pre- and Postoperative Acoustic Outcomes in Thyroid Surgery

Run by Fujian Medical University · NCT06254859 · Data updated 2026-11-12

This study tests whether using nerve monitoring during thyroid surgery can help improve voice quality for patients after the operation.

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Quick facts

Study typeObservational
SexAll
Enrollment100 (estimated)
SponsorFujian Medical University
Academic / other
Locations1 site (Fuzhou, Fujian)
StatusRecruiting
StartedMarch 1, 2024
Main results expectedDecember 31, 2025
Study endsDecember 31, 2025
Registry record updatedMay 20, 2025
Trial IDNCT06254859 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 20-60 scheduled for conventional unilateral thyroid lobectomy with isthmus resection and central compartment lymph node dissection.

Probably not a fit

Patients with a history of head and neck surgeries, vocal cord disorders, or neurological conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study examines how changes in intraoperative recurrent laryngeal nerve monitoring signals affect the voice quality of patients undergoing thyroid surgery. By analyzing surgical data and postoperative voice recordings, the research aims to identify patterns in these signals and their correlation with voice outcomes. The goal is to enhance surgical practices and improve patient well-being by providing insights into nerve function during surgery. This comprehensive analysis seeks to contribute valuable knowledge to the field of thyroid surgery.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical techniques that enhance voice quality after thyroid surgery.

How similar studies have gone: Other studies have shown success in using intraoperative nerve monitoring to improve surgical outcomes, indicating a promising approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age 20-60 years old.
* Planned conventional unilateral thyroid lobectomy + isthmus resection + central compartment lymph node dissection.

Exclusion Criteria:

* History of past head and neck surgeries.
* Pronunciation system defect and disorder history.
* History of vocal cord polyps or nodules.
* History of upper respiratory tract infection in the 2 weeks before surgery or postoperative infection history.
* History of neurological disorders.
* Abnormalities in the throat.
* Preoperative damage to throat morphology or motor function.
* Preoperative functional voice or language disorders, noticeable hoarseness, or difficulty in pronunciation.
* Pre- and postoperative laryngoscopic examination showing vocal cord paralysis and arytenoid joint dislocation.
* Neurological disorders causing abnormal throat function.
* Patient unable to cooperate with VHI (Voice Handicap Index) assessment and voice spectrum examination.

Where it's running

  • Fujian Medical University Union Hospital
    Fuzhou, Fujian, China
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.