Impact of Hemodialysis on Emotions and Cognitive Functions in Kidney Failure Patients
Study on the Changes of Emotion and Cognitive Function and Brain Imaging in Uremic Patients Before and After Entering Dialysis
This study looks at how starting hemodialysis affects the feelings and thinking skills of kidney failure patients and checks for changes in their brain structure before and after treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Beijing Friendship Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing) |
| Trial ID | NCT05137470 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess how starting hemodialysis treatment affects the emotional and cognitive functions of patients with end-stage renal disease (ESRD). It will also investigate changes in brain structure through magnetic resonance imaging (MRI) before and after treatment. The study will collect demographic and clinical data, including various health indicators and quality of life measures, to identify relevant clinical risk factors and potential therapeutic targets. Participants will include both new and long-term hemodialysis patients at Beijing Friendship Hospital.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who are either new to hemodialysis or have been on hemodialysis for at least six months.
Not a fit: Patients with severe pre-existing central nervous system diseases or those unable to complete MRI examinations will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of emotional and cognitive challenges faced by kidney failure patients undergoing hemodialysis.
How similar studies have performed: While there have been studies examining cognitive and emotional impacts of chronic illnesses, this specific focus on hemodialysis patients using MRI is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who are new to hemodialysis treatment, and those who are on regular hemodialysis treatment for ≥6 months. * Age ≥ 18 years old. Exclusion Criteria: * There was already a severe central nervous system disease before dialysis. * Hearing and visual impairment cannot communicate or cooperate. * Mental illness and incapacity. * The magnetic resonance examination could not be completed for various reasons. * Life expectancy with serious diseases is less than 6 months.
Where this trial is running
Beijing, Beijing
- Beijing Friendship Hospital, Capital Medical University — Beijing, Beijing, China (Recruiting)
Study contacts
- Study coordinator: XU LIU, master
- Email: liuxu_000@sina.com
- Phone: +86-010-63138579
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.