Impact of eradicating Helicobacter pylori on GERD symptoms

Effect of Helicobacter Pylori Eradication on Gastroesophageal RefIux Disease (GERD)

Observational Assiut University · NCT06457334

This study is testing if getting rid of Helicobacter pylori can help people with GERD feel better.

Quick facts

Study typeObservational
Enrollment100 (estimated)
SexAll
SponsorAssiut University Academic / other
Locations1 site (Asyut)
Trial IDNCT06457334 on ClinicalTrials.gov

What this trial studies

This observational study evaluates how the eradication of Helicobacter pylori affects symptoms of gastroesophageal reflux disease (GERD). GERD is a chronic condition characterized by the regurgitation of stomach contents, leading to discomfort and a reduced quality of life. The study aims to clarify the unclear relationship between H. pylori infection and GERD, particularly whether eradicating the bacterium can improve GERD symptoms. Patients diagnosed with GERD will be included, and the study will assess symptom changes following H. pylori eradication.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with GERD, both clinically and endoscopically.

Not a fit: Patients who do not have a diagnosis of GERD will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into a new treatment approach for improving GERD symptoms through H. pylori eradication.

How similar studies have performed: Previous studies have suggested an inverse relationship between H. pylori infection and GERD, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients diagnosed as GERD clinically and endscopically.

Exclusion Criteria:

* NO exclusion criteria

Where this trial is running

Asyut

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions GERDHelicobacter pylori
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.