Impact of Different Pacing Sites in Patients with Bradyarrhythmias and Heart Failure

Clinical Study of Impact of Different Pacing Site in Patients

Observational Second Affiliated Hospital, School of Medicine, Zhejiang University · NCT04931550

This study is trying to see if pacing the heart from different spots can help people with slow heartbeats and heart failure feel better and have better long-term results.

Quick facts

Study typeObservational
Enrollment600 (estimated)
Ages18 Years to 100 Years
SexAll
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University Academic / other
Locations1 site (Hangzhou, Zhejiang)
Trial IDNCT04931550 on ClinicalTrials.gov

What this trial studies

This observational study investigates the efficacy and safety of cardiac pacing at various sites in patients with bradyarrhythmias and heart failure. It aims to compare the long-term outcomes of pacing from different anatomical locations, including the right atrial appendage, His bundle, and left ventricular pacing via coronary veins. By analyzing data from patients who have undergone pacemaker implantation, the study seeks to identify the advantages and disadvantages of each pacing site. The findings could provide valuable insights into optimizing pacing strategies for better patient outcomes.

Who should consider this trial

Good fit: Ideal candidates include patients who have received pacemaker implantation at the Second Hospital of Zhejiang Medical University and can understand and cooperate with the study.

Not a fit: Patients who are unable to understand the study or unwilling to provide informed consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the management of bradyarrhythmias and heart failure by identifying the most effective pacing sites.

How similar studies have performed: There is limited existing research comparing the long-term efficacy of different pacing sites, making this study a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients who received pacemaker implantation in the Second Hospital of Zhejiang Medical University by Pan Xiaohong and other surgeons.
* Patients who have the ability to understand the test and can cooperate with investigators.

Exclusion Criteria:

* Patients who unable to understand or unwilling to fill in informed consent forms or follow visitors.

Where this trial is running

Hangzhou, Zhejiang

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions BradyarrhythmiasHeart FailurePacemaker
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.