Impact of Body Mass Index on Knee Surgery Outcomes
The Effect of Body Mass Index on Short-term Results of HTO for Treatment of OA With Varus Knee in Upper Egypt Population
This study is testing how body weight affects the recovery and results of knee surgery in people with knee osteoarthritis who haven't found relief from other treatments.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | All |
| Sponsor | Egymedicalpedia Industry-sponsored |
| Locations | 1 site (Asyut) |
| Trial ID | NCT06590818 on ClinicalTrials.gov |
What this trial studies
This study investigates how body mass index (BMI) affects the short-term results of high tibial osteotomy (HTO) in patients with knee osteoarthritis, particularly those with varus knee alignment. It aims to identify the relationship between obesity and surgical outcomes, focusing on patients who have not responded to conservative treatments. The study will include patients diagnosed with knee osteoarthritis who meet specific criteria regarding their knee condition and overall health. By analyzing the outcomes, the research seeks to provide insights into optimizing surgical interventions for this population.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with knee osteoarthritis who have a varus knee alignment and have not found relief from conservative treatments.
Not a fit: Patients with severe obesity (BMI > 35 kg/m²) or those with knee osteoarthritis due to infections or autoimmune diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes for patients with knee osteoarthritis, particularly those with varying BMI levels.
How similar studies have performed: Other studies have explored the impact of BMI on surgical outcomes in orthopedic procedures, indicating a potential for success in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Meet the diagnostic criteria for knee osteoarthritis and only have one knee * No serious underlying medical disease * Conservative treatment is ineffective and there is a willingness for surgery * X-ray shows degeneration limited to the medial joint space (Ahlback grade ≥ grade II) * Knee flexion range of motion \> 90°, varus deformity \< 15°, flexion contracture \< 5°. * Clinical examination shows intact anterior cruciate ligament and collateral ligament, tenderness point is limited to the medial joint space, and the lateral compartment and patellofemoral joint are intact. Exclusion Criteria: * knee osteoarthritis caused by infection, blood-related or autoimmune diseases. * severe obesity (BMI\>35 kg/m 2 ) or morbid obesity (obesity caused by diseases such as hypercortisolism and hypothyroidism, BMI≥30 kg/m 2 ).
Where this trial is running
Asyut
- Al-Azhar University hospitals — Asyut, Egypt (Recruiting)
Study contacts
- Study coordinator: Ahmed Ramadan Hammad, MSC
- Email: addamobil852@gmail.com
- Phone: 01141249007
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.