Impact of antioxidant supplements on sperm health and fertility
Kocaeli University
This study is testing if an antioxidant supplement can improve sperm health and fertility in men aged 20-40 who have been struggling with infertility for over a year.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 20 Years to 40 Years |
| Sex | Male |
| Sponsor | Kocaeli University Academic / other |
| Locations | 1 site (Kocaeli, Izmit) |
| Trial ID | NCT05826782 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of an antioxidant food supplement on sperm proteomic structure and semen parameters in men experiencing asthenozoospermia, a common cause of male infertility. Participants aged 20-40 who have been infertile for at least 12 months will receive either the antioxidant supplement or a placebo. The study aims to determine if the antioxidant treatment can improve sperm motility and overall fertility outcomes by addressing oxidative stress-related damage. The research is based on previous findings that suggest antioxidants may enhance semen quality.
Who should consider this trial
Good fit: Ideal candidates are men aged 20-40 who have been diagnosed with asthenozoospermia and have normal hormonal values and physical examinations.
Not a fit: Patients with previous infertility treatments, chronic illnesses, or those who smoke or have alcohol addiction may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new dietary intervention to improve sperm motility and enhance fertility in men with asthenozoospermia.
How similar studies have performed: Previous studies have shown positive effects of antioxidant supplementation on semen parameters, indicating potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Being in the age range of 20-40 2. Be infertile ( 12 months intercourse without any contraception) 3. Due to infertility, you should apply to us and have a spermiogram detection of asthenozoospermia 4. Patients whose spouses have normal gynecological examinations 5. Patients with normal physical examinations 6. Patients with normal hormonal values (FSH, LH,PRL,Testosterone,Estrogen) - Exclusion Criteria: 1. previous treatment for infertility 2. Previously due to infertility or for any reason take antioxidant food supplements 3. Surgery or physical examination due to varicocele detection of varicocele 4. Detection of endocrine disorder (Defect in serum blends) 5. Smokers and alcohol addiction 6. Detection of infection in the genital tract 7. Having a chronic illness -
Where this trial is running
Kocaeli, Izmit
- Naci Burak Çinar — Kocaeli, Izmit, Turkey (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.