Impact of air quality on early coronary artery disease
Influence of Air Quality on the Development and Progression of Premature Coronary Artery Disease
This study looks at how air pollution affects the early development of heart disease in people aged 18 to 40.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4272 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | Fundacin Biomedica Galicia Sur Academic / other |
| Locations | 1 site (Vigo, Pontevedra) |
| Trial ID | NCT06464042 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate how environmental pollutants affect the early onset and progression of coronary artery disease (CAD) in individuals aged 18 to 40. By employing a retrospective analytical case-control design, the study will analyze data from patients with a history of CAD and compare it to a control group without such a diagnosis. The research will also consider gender differences in the impact of air quality on CAD. The findings could provide valuable insights into the relationship between air pollution and heart health in younger populations.
Who should consider this trial
Good fit: Ideal candidates for this study are men and women aged 18 to 40 with a diagnosis of coronary artery disease.
Not a fit: Patients over 40 years old or those without a diagnosis of coronary artery disease are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved public health policies aimed at reducing air pollution and its associated risks for young individuals with coronary artery disease.
How similar studies have performed: Other studies have indicated a correlation between air pollution and cardiovascular diseases, suggesting that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
CASES: Inclusion Criteria: * Women and men between 18 and 40 years old with a diagnosis of coronary artery disease coded in their medical records in Galicia Exclusion Criteria: * Not having a postal code and primary care center assigned in their medical records in Galicia CONTROL Inclusion Criteria: * Women and men between 18 and 40 years old with no diagnosis or history of CAD or other coronary disease coded in their medical records Exclusion Criteria: * Present with non-ischemic coronary diseas. * Have a serious condition that affects or decreases life expectancy. * Do not have a postal code or primary care center assigned in their medical records in Galicia
Where this trial is running
Vigo, Pontevedra
- Hospital Álvaro Cunqueiro — Vigo, Pontevedra, Spain (Recruiting)
Study contacts
- Principal investigator: Pablo Juan-Salvadores, Pharma, PhD — Instituto de Investigación Sanitaria Galicia Sur (IIS Galicia Sur)
- Study coordinator: Pablo Juan-Salvadores, Pharma, PhD
- Email: pablo.juan@iisgaliciasur.es
- Phone: +34986825564
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.