Impact of a specific nerve block on pain management during gallbladder surgery
Effects of External Oblique Intercostal Plane Block Applied in Laparoscopic Cholecystectomy Surgery on Intraoperative Opioid ConsumptionDetermined by ANI (Analgesia Nociceptive Index) and Postoperative Analgesia Quality Guide; A Randomized Controlled Trial
This study is testing if a specific nerve block can help reduce the need for pain medication during gallbladder surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | Samsun University Academic / other |
| Locations | 1 site (Samsun, İ̇lkadim) |
| Trial ID | NCT06869837 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of an external oblique intercostal plane block (EOIPB) in reducing opioid consumption during laparoscopic cholecystectomy surgery. Participants will be divided into two groups: those receiving the nerve block and those who do not. The study will monitor various parameters, including pulse, mean arterial pressure, oxygen saturation, and the Analgesia Nociception Index (ANI), to assess pain management and opioid needs. The goal is to maintain the ANI within a target range of 50-70 while adjusting remifentanil levels accordingly.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-70 undergoing elective laparoscopic cholecystectomy with ASA physical status I-II and a BMI under 35.
Not a fit: Patients with routine analgesic use, coagulopathy, local anesthetic allergies, cardiac arrhythmias, or those classified as ASA III and above may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce opioid consumption and improve pain management for patients undergoing gallbladder surgery.
How similar studies have performed: Other studies have shown promising results with similar regional anesthesia techniques, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants who will undergo elective laparoscopic cholecystectomy surgery, * Age 18-70, * ASA I-II physical status, * Body mass index (BMI) \< 35 kg/m², * Participants who have written consent to participate in the study Exclusion Criteria: * Participants with routine analgesic consumption, * Those with coagulopathy, * Those with a history of local anesthetic allergy, * Those with cardiac arrhythmia and pacemaker, * ASA III and above, Those with dementia
Where this trial is running
Samsun, İ̇lkadim
- Samsun University, Samsun Training and Research Hospital — Samsun, İ̇lkadim, Turkey (Recruiting)
Study contacts
- Study coordinator: Hale K Celik
- Email: ck_hale@hotmail.com
- Phone: 0905057242409
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.