Impact of a Chronobiologic Feeding Model on Newborn Circadian Rhythm

Effect of Chronobıologıcal Approach Feedıng Model on Cırcadıan Rhythm, Growth and Physıologıcal Parameters in Newborn: A Randomızed Controlled Study

Not applicable Interventional Selcuk University · NCT05923437

This study is testing if a special feeding schedule for newborns can help improve their sleep patterns and growth during those important early weeks of life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages28 Weeks to 42 Weeks
SexAll
SponsorSelcuk University Academic / other
Locations2 sites (Kirsehir and 1 other locations)
Trial IDNCT05923437 on ClinicalTrials.gov

What this trial studies

This study evaluates how a feeding model based on chronobiology affects the circadian rhythm, growth, and physiological parameters in newborns. It focuses on the critical early weeks of life when establishing a healthy sleep pattern is essential for the development of the circadian rhythm. The study will involve newborns receiving breast milk at regular intervals, aiming to understand how this feeding approach influences their sleep-wake cycles and overall development. The research highlights the importance of nutrition and environmental factors in shaping newborns' circadian rhythms.

Who should consider this trial

Good fit: Ideal candidates for this study are newborns with a gestational age between 28-42 weeks, stable health conditions, and who are exclusively breastfed at 3-hour intervals.

Not a fit: Patients who may not benefit from this study include those with congenital anomalies, central nervous system dysfunction, or those requiring resuscitation.

Why it matters

Potential benefit: If successful, this study could enhance the understanding of how feeding practices influence the circadian rhythm and overall health of newborns.

How similar studies have performed: While there is limited research on the relationship between circadian rhythm and breast milk, this study aims to fill a gap in existing literature, making it a novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Gestational age between 28-42 weeks
* Birth weight between 1500 and 4200 gr
* Hospitalization for at least 3 days
* Exclusive breastfeeding (oral/ enteral)
* Feeding at 3-hour intervals
* Stable health condition
* Spontaneous breathing

Exclusion Criteria:

* Babies fed outside of 3-hour intervals (hourly or two-hourly intervals)
* 5th minute apgar score below 4 at the time of delivery
* Resuscitation requirement
* Having a congenital anomaly
* Interventional intervention in the head region
* Central nervous system dysfunction
* Postpartum medical complications

Where this trial is running

Kirsehir and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Breast Feeding, ExclusiveHospitalizationFeeding PatternsBreast milkNutritionNursingChronobiologyCircadian rhythm
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.