Impact of 24-hour shifts on immune function in surgery residents
Official title: Impact of a 24-hour Shift Call on the Immune Status of Surgery Residents
Run by University of Chicago · NCT06636318 · Data updated 2026-11-12
This study tests how working 24-hour shifts affects the immune system of surgery residents by looking at their blood samples and health data.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Status | Recruiting |
| Started | October 17, 2024 |
| Main results expected | December 2027 |
| Study ends | December 2027 |
| Registry record updated | December 9, 2025 |
| Trial ID | NCT06636318 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy surgery residents aged 18 and older who are currently undergoing 24-hour shift rotations.
✕Probably not a fit
Patients who are not surgery residents or those with underlying health conditions that affect immune function may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the effects of sleep deprivation on the immune system of surgery residents who work 24-hour shifts. It aims to assess changes in inflammatory responses and immune cell function by analyzing blood samples and biometric data. The study hypothesizes that sleep deprivation leads to increased inflammatory cytokines and decreased immune cell activity, providing valuable insights into the health implications for medical professionals under such conditions.
Why it matters
Potential benefit: If successful, this study could help identify the health risks associated with sleep deprivation in medical professionals and inform strategies to mitigate these effects.
How similar studies have gone: Previous studies have indicated that sleep deprivation adversely affects immune function, suggesting that this approach is supported by existing literature.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy subjects * Surgery residents in a 24-hour shift rotation * Gender of subjects: Males and females * Age of subjects: 18 years old and older * Racial and Ethnic Origin: Any race or ethnicity Exclusion Criteria: * Unwilling/unable to sign informed consent * Vulnerable Subjects/Subject Capacity to provide consent
Where it's running
-
The University of Chicago
Chicago, Illinois, United States Recruiting
Study contacts
- Principal investigator: Angelica Perez-Gutierrez, MD — University of Chicago
- Study coordinator: Angelica Perez-Gutierrez, MD
- Email: rperezgutierrez@bsd.uchicago.edu
- Phone: 773-834-5087
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.