Impact of 24-hour shifts on immune function in surgery residents
Impact of a 24-hour Shift Call on the Immune Status of Surgery Residents
This study tests how working 24-hour shifts affects the immune system of surgery residents by looking at their blood samples and health data.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT06636318 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the effects of sleep deprivation on the immune system of surgery residents who work 24-hour shifts. It aims to assess changes in inflammatory responses and immune cell function by analyzing blood samples and biometric data. The study hypothesizes that sleep deprivation leads to increased inflammatory cytokines and decreased immune cell activity, providing valuable insights into the health implications for medical professionals under such conditions.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy surgery residents aged 18 and older who are currently undergoing 24-hour shift rotations.
Not a fit: Patients who are not surgery residents or those with underlying health conditions that affect immune function may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify the health risks associated with sleep deprivation in medical professionals and inform strategies to mitigate these effects.
How similar studies have performed: Previous studies have indicated that sleep deprivation adversely affects immune function, suggesting that this approach is supported by existing literature.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy subjects * Surgery residents in a 24-hour shift rotation * Gender of subjects: Males and females * Age of subjects: 18 years old and older * Racial and Ethnic Origin: Any race or ethnicity Exclusion Criteria: * Unwilling/unable to sign informed consent * Vulnerable Subjects/Subject Capacity to provide consent
Where this trial is running
Chicago, Illinois
- The University of Chicago — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Angelica Perez-Gutierrez, MD — University of Chicago
- Study coordinator: Angelica Perez-Gutierrez, MD
- Email: rperezgutierrez@bsd.uchicago.edu
- Phone: 773-834-5087
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.