Clinical trial Recruiting at 1 site Observational Ages 18 and up

Impact of 24-hour shifts on immune function in surgery residents

Official title: Impact of a 24-hour Shift Call on the Immune Status of Surgery Residents

Run by University of Chicago · NCT06636318 · Data updated 2026-11-12

This study tests how working 24-hour shifts affects the immune system of surgery residents by looking at their blood samples and health data.

More Sleep Deprivation trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorUniversity of Chicago
Academic / other
Locations1 site (Chicago, Illinois)
StatusRecruiting
StartedOctober 17, 2024
Main results expectedDecember 2027
Study endsDecember 2027
Registry record updatedDecember 9, 2025
Trial IDNCT06636318 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy surgery residents aged 18 and older who are currently undergoing 24-hour shift rotations.

Probably not a fit

Patients who are not surgery residents or those with underlying health conditions that affect immune function may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effects of sleep deprivation on the immune system of surgery residents who work 24-hour shifts. It aims to assess changes in inflammatory responses and immune cell function by analyzing blood samples and biometric data. The study hypothesizes that sleep deprivation leads to increased inflammatory cytokines and decreased immune cell activity, providing valuable insights into the health implications for medical professionals under such conditions.

Why it matters

Potential benefit: If successful, this study could help identify the health risks associated with sleep deprivation in medical professionals and inform strategies to mitigate these effects.

How similar studies have gone: Previous studies have indicated that sleep deprivation adversely affects immune function, suggesting that this approach is supported by existing literature.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy subjects
* Surgery residents in a 24-hour shift rotation
* Gender of subjects: Males and females
* Age of subjects: 18 years old and older
* Racial and Ethnic Origin: Any race or ethnicity

Exclusion Criteria:

* Unwilling/unable to sign informed consent
* Vulnerable Subjects/Subject Capacity to provide consent

Where it's running

  • The University of Chicago
    Chicago, Illinois, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.