ImmunoPET imaging for solid tumors targeting Trop2

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to optimize a new imaging method called Trop2-targeted immunoPET/CT for diagnosing solid tumors. It will evaluate the physiological and pathological distribution of imaging agents in various types of solid tumors, including bladder and prostate cancers. Patients with confirmed or suspected solid tumors will undergo whole-body scans after receiving a tracer injection, and the study will assess the diagnostic efficacy of this new imaging approach compared to conventional methods. The correlation between tumor uptake and Trop2 expression levels will also be analyzed.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged 18-75 year-old and of either sex
* Histologically confirmed diagnosis of solid tumors (including uroepithelial cancer, bladder cancer, prostate cancer, lung cancer, nasopharyngeal cancer, liver cancer, cholangiocarcinoma, ovarian cancer, cervical cancer, endometrial cancer, thyroid cancer, head and neck cancer) or suspected solid tumors (including uroepithelial cancer, bladder cancer, prostate cancer, lung cancer, nasopharyngeal cancer, liver cancer, cholangiocarcinoma, ovarian cancer, cervical cancer, endometrial cancer, thyroid cancer, head and neck cancer) by diagnostic imaging;
* Capable of giving signed informed consent, including compliance with the requirements and restrictions in the informed consent form (ICF) and this protocol.

Exclusion Criteria:

* Pregnancy；
* Severe hepatic and renal insufficiency;
* Allergic to single-domain antibody radiopharmaceuticals.

Where it's running

• Renji Hospital, School of Medicine, Shanghai Jiao Tong University
  Shanghai, China Recruiting

Study contacts

• Principal investigator: Weijun Wei, Ph.D. & M.D. — Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University
• Study coordinator: Weijun Wei, Ph.D. & M.D.
• Email: wwei@shsmu.edu.cn
• Phone: 15000083153

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.