Immune and breathing measurements in children with Down syndrome and pneumonia

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a descriptive, cross-sectional analysis of baseline data from 40 children with Down syndrome enrolled before an intervention. Investigators measured serum IgG, IgA, and IgM by nephelometry, total white blood cell count by automated analyzer, respiratory rate by manual count, and oxygen saturation by pulse oximetry. They used Pearson or Spearman correlation tests to examine relationships among immune markers, respiratory parameters, and age. The analysis aims to characterize associations at presentation rather than to test a treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Down Syndrome with acute bronchopneumonia
* sufficient cognitive ability

Exclusion Criteria:

* severe congenital heart defects
* primary immunodeficiencies

Where it's running

• Badr university
  Cairo, Egypt Recruiting
• Mona Mohamed Abdelkhalek
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mona Mohamed Abdelkhalek, assistance prof
• Email: 3m.sons@gmail.com
• Phone: 002021024056108

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.