Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Immediate neck manual therapy effects on atlas position and neck muscles

Official title: Immediate Neuromuscular Responses of the Obliquus Capitis Inferior Following Upper Cervical Manual Therapy

Run by Florida Gulf Coast University · NCT07725198 · Data updated 2026-11-12

This trial tests two upper neck manual therapy techniques to see their immediate effect on neck alignment, atlas position, and a neck muscle shape in adults with head and neck pain or headaches.

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Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment80 (estimated)
SponsorFlorida Gulf Coast University
Academic / other
Locations1 site (Fort Myers, Florida)
StatusRecruiting
StartedMay 1, 2025
Main results expectedJanuary 1, 2027
Study endsJanuary 1, 2027
Registry record updatedAugust 28, 2026
Trial IDNCT07725198 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults who understand English and have no prior cervical spine surgery or traumatic cervical injury and no contraindications to cervical manual therapy.

Probably not a fit

Patients with conditions that negate manual therapy safety or those who do not respond to upper cervical interventions may not experience benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, repeated-measures study examines the immediate effects of thrust long-axis manipulation of the C1-C2 junction on craniovertebral alignment and the obliquus capitis inferior muscle. Participants undergo two upper cervical manual therapy interventions with measurements captured right away to assess changes in CVA, atlas position, and OCI morphology using ultrasound. The design allows within-subject comparison of the interventions to determine short-term biomechanical responses. The study is conducted at Florida Gulf Coast University and does not report a multi-site or powered comparative framework.

Why it matters

Potential benefit: If successful, the findings could help clinicians choose manual therapy approaches that optimize neck alignment and muscle response in patients with head and neck symptoms.

How similar studies have gone: Earlier research in manual therapy and cervical muscle responses has shown short-term biomechanical changes with similar techniques, though results can vary by individual.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* read and understand English
* no previous history of cervical spine surgery or traumatic cervical injury
* no contraindications to cervical manual therapy

Exclusion Criteria:

* any absolute contraindications to cervical manipulation
* any other medical condition considered unsafe for manual therapy.

Where it's running

  • Florida Gulf Coast University Marieb Hall 101
    Fort Myers, Florida, United States
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.