Clinical trial Recruiting at 1 site Early Phase 1 Interventional Ages 18 and up

Imaging tumors using a new dual-target agent

Official title: 68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor Patients

Run by Peking Union Medical College Hospital · NCT05549024 · Data updated 2026-11-12

This study is testing a new imaging agent to see if it can help doctors get a clearer picture of tumors in patients with breast, brain, and prostate cancers compared to standard imaging methods.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Ages18 Years and up
SexAll
Enrollment90 (estimated)
SponsorPeking Union Medical College Hospital
Academic / other
Locations1 site (Beijing)
StatusRecruiting
StartedAugust 16, 2022
Main results expectedDecember 31, 2025
Study endsDecember 31, 2026
Registry record updatedJuly 5, 2024
Trial IDNCT05549024 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include patients with confirmed or suspected breast, brain, or prostate cancer who can provide informed consent.

Probably not a fit

Patients who are pregnant, breastfeeding, or have medical conditions that may interfere with study compliance will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of a novel dual-target imaging agent, 68Ga-RM26-RGD, for PET/CT imaging in patients with breast, brain, and prostate cancers. The approach aims to improve tumor visualization by targeting specific receptors that are highly expressed in malignant tissues and their associated neovascularization. By comparing this new agent with conventional imaging methods, the study seeks to enhance diagnostic accuracy for tumors that typically show low uptake in standard imaging. Patients will undergo PET/CT scans using both the new agent and traditional imaging agents to assess the clinical application value of this dual-target approach.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic accuracy for certain types of cancer, allowing for better treatment planning.

How similar studies have gone: While conventional imaging methods have been widely used, this dual-target approach is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with confirmed or suspected breast/brain/prostate cancer;
* 68Ga-RM26-RGD and 18F-FDG(or 68Ga-RM26 or 68Ga-RGD) PET/CT within 2 week;
* signed written consent.

Exclusion Criteria:

* pregnancy;
* breastfeeding;
* any medical condition that in the opinion of the investigator may significantly interfere with study compliance.

Where it's running

  • Peking Union Medical College Hospital
    Beijing, China
    Recruiting

Study contacts

  • Principal investigator: Zhaohui Zhu, MD,PHD — Peking Union Medical College Hospital
  • Study coordinator: Zhaohui Zhu, MD,PHD
  • Email: 13611093752@163.com
  • Phone: 86+13611093752

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.