Identifying the best treatment for aortic valve disease
Clinical Cohort Study - Hamburg AoRtic Valve cOhoRt
Universitätsklinikum Hamburg-Eppendorf · NCT04227002
This study is trying to find the best treatment for people with severe aortic valve disease by looking at their individual health factors and how different treatments work for them.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 15000 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf (other) |
| Locations | 1 site (Hamburg) |
| Trial ID | NCT04227002 on ClinicalTrials.gov |
What this trial studies
This observational study aims to determine the optimal treatment approach for patients suffering from aortic valve disease by evaluating individual risk profiles and expected clinical outcomes. It will analyze the relationship between demographic factors, procedural data, and biomarkers with clinical outcomes in a prospective manner. The study will include patients with severe aortic valve disease, such as aortic stenosis and regurgitation, to better understand predictors of outcomes and improve risk prediction for various treatment options, including surgical and transcatheter interventions.
Who should consider this trial
Good fit: Ideal candidates are patients with clinically relevant aortic valve disease who can provide informed consent and understand German.
Not a fit: Patients who are unable to understand or write in German or those with physical or psychological conditions preventing participation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more personalized and effective treatment strategies for patients with aortic valve disease.
How similar studies have performed: While the approach of optimizing treatment for aortic valve disease is being explored, this specific study's methodology is novel in its comprehensive assessment of individual risk factors and outcomes.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with clinically relevant aortic valve disease (aortic valve stenosis, aortic regurgitation, degenerated aortic valve prosthesis) * Written informed consent Exclusion Criteria: * Insufficient knowledge of the German language (able to understand and write the German language) * Physical or psychological incapability to take part in the investigation
Where this trial is running
Hamburg
- Universitäres Herz- und Gefäßzentrum — Hamburg, Germany (RECRUITING)
Study contacts
- Principal investigator: Moritz Seiffert, MD — University Heart Center Hamburg
- Study coordinator: Moriz Seiffert, MD
- Email: m.seiffert@uke.de
- Phone: +49407410
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Aortic Valve Stenosis