Identifying stillbirth risk using ultrasound
Stillbirth Risk Identification Using Multiparametric Ultrasound
This study is testing a new way to use ultrasound to see if it can help identify risks for stillbirth by checking the placenta in pregnant women between 35 and 37 weeks.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 282 (estimated) |
| Ages | 19 Years and up |
| Sex | Female |
| Sponsor | University of British Columbia Academic / other |
| Locations | 1 site (Vancouver, British Columbia) |
| Trial ID | NCT06930274 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify a novel biomarker for stillbirth by predicting perinatal hypoxia through quantitative ultrasound of the placenta between 35 and 37 weeks of gestation. The study collects raw radio frequency data during ultrasounds using a handheld device and analyzes it to derive QUS-P parameters. The goal is to enable early identification of perinatal hypoxia, allowing for timely interventions to prevent serious complications such as encephalopathy and stillbirth.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant individuals aged 19 years or older, carrying a singleton fetus, and planning to deliver at BC Women's Hospital before 38 weeks of gestation.
Not a fit: Patients who are pregnant with multiples or those who are not planning to deliver at BC Women's Hospital will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could significantly reduce the incidence of stillbirth by enabling earlier detection and intervention for at-risk pregnancies.
How similar studies have performed: Other studies have shown promise in using ultrasound for similar predictive purposes, but this specific approach using quantitative ultrasound from the placenta is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Pregnant with singleton 2. Age 19 years or older 3. Provision of informed consent 4. Planning to deliver at BC Women's Hospital 5. 38 weeks gestation or less Exclusion Criteria: 1. Pregnant with multiples 2. Not planning to deliver at BC Women's Hospital 3. Less than 19 years of age 4. Greater than 38 weeks gestation
Where this trial is running
Vancouver, British Columbia
- South Community Birth Program — Vancouver, British Columbia, Canada (Recruiting)
Study contacts
- Principal investigator: Robert Rohling, PhD — The University of British Columbia
- Study coordinator: Tiffany Reeve, MSc
- Email: treeve@mail.ubc.ca
- Phone: 778-227-1243
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.