Identifying risks of heart failure and cognitive decline in people with type 2 diabetes
Official title: Prediction of Heart Failure and Cognitive Decline in Type 2 Diabetes : Longitudinal Cohort Study of Immuno-inflammation, Cardiac Energetics and Cognition.PreciDIAB-HEART&BRAIN
Run by University Hospital, Lille · NCT04583800 · Data updated 2026-11-12
This study is trying to find out which adults with type 2 diabetes might be at risk for heart failure and memory problems so that they can get early help.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 600 (estimated) |
| Sponsor | University Hospital, Lille Academic / other |
| Locations | 1 site (Lille) |
| Status | Recruiting |
| Started | June 22, 2021 |
| Main results expected | June 2026 |
| Study ends | June 2026 |
| Registry record updated | December 23, 2025 |
| Trial ID | NCT04583800 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults with type 2 diabetes who are free of heart failure at stage B.
✕Probably not a fit
Patients with dementia or those who already meet criteria for heart failure at stage B will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to identify patients with type 2 diabetes who are at risk of developing heart failure and cognitive decline. By focusing on early detection, the study seeks to develop personalized preventive strategies for these conditions. Participants will be adults with type 2 diabetes who do not have heart failure at stage B or dementia. The study will gather data to better understand the relationship between diabetes and these serious health issues.
Why it matters
Potential benefit: If successful, this study could lead to targeted prevention strategies for heart failure and cognitive decline in diabetic patients.
How similar studies have gone: While the approach of identifying risks in diabetic patients is established, the specific focus on early heart failure and cognitive decline in this context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults * Persons able to understand and object to the information provided. * Type 2 diabetic patient free of heart failure ≥stade B * Patient affiliated with a social security scheme. * Patient agreeing to sign the informed consent form Exclusion Criteria: * Patient with dementia * Patient with at least one of the criteria for heart failure ≥stade B
Where it's running
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Hopital Roger Salengro, CHU Lille
Lille, France Recruiting
Study contacts
- Principal investigator: Charlotte Cordonnier, MD,PhD — University Hospital, Lille
- Study coordinator: Charlotte Cordonnier, MD,PhD
- Email: precidiab_heart_brain@chru-lille.fr
- Phone: 0320445962
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Cognitive screening and multidomain care to slow memory and thinking decline in older adults with type 2 diabetes
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This study is testing if data from Apple Watches can help predict heart failure problems and the chances of needing to go back to the hospital for patients with heart failure.
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This study is testing which diabetes medication, empagliflozin or dapagliflozin, works better for people with type 2 diabetes, chronic kidney disease, and heart failure.
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This study is testing whether the Aortix device can help people with acute heart failure who aren't responding to diuretics feel better compared to standard treatment.
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This study is trying to find specific markers in the blood of people with Type 2 Diabetes and heart failure to see if they can help predict who will benefit from a heart treatment.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.