Clinical trial Recruiting at 1 site Interventional Ages 18 to 39

Identifying optimal work/rest cycles for military missions in heat

Official title: Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat

Run by State University of New York at Buffalo · NCT06475339 · Data updated 2026-11-12

This study is testing different work and rest schedules for military missions in hot weather to see which ones help soldiers perform better and stay safe from heat-related issues.

Quick facts

Study typeInterventional
Ages18 Years to 39 Years
SexAll
Enrollment24 (estimated)
SponsorState University of New York at Buffalo
Academic / other
Locations1 site (Buffalo, New York)
StatusRecruiting
StartedNovember 1, 2024
Main results expectedMarch 2027
Study endsMarch 2027
Registry record updatedJanuary 26, 2026
Trial IDNCT06475339 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are healthy, physically active individuals without significant medical histories.

Probably not a fit

Patients with cardiovascular, metabolic, respiratory, or other significant health issues may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to determine effective work/rest cycles that enhance mission completion speed while reducing heat strain and neuromuscular fatigue in emergency situations. By comparing various work/rest intervals, the study seeks to find a balance between performance and safety during high-temperature operations. The findings will assist military leaders in making informed decisions regarding mission planning in hot weather, ultimately improving operational success and reducing heat-related casualties.

Why it matters

Potential benefit: If successful, this study could lead to improved safety and performance for military personnel operating in extreme heat conditions.

How similar studies have gone: While similar studies have explored exercise and heat strain, this specific approach to optimizing work/rest cycles in military contexts is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy individuals
* Physically active

Exclusion Criteria:

* History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease
* Hypertensive (systolic blood pressure \> 139 mmHg, diastolic blood pressure \> 89 mmHg) or tachycardic (heart rate \> 100 bpm) during the screening visit
* Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin)
* Tobacco or nicotine use currently or in the past six months
* Musculoskeletal injury expected to impact exercise in the protocol
* A positive pregnancy test at any point in the study
* Study physician discretion based on any other medical condition or medication
* Inability to understand or follow instructions or the protocol
* Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.

Where it's running

  • Center for Research and Education in Special Environments
    Buffalo, New York, United States
    Recruiting

Study contacts

  • Principal investigator: Riana R Pryor, PhD — University at Buffalo
  • Study coordinator: Riana R Pryor, PhD
  • Email: rpryor@buffalo.edu
  • Phone: 7168295456

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.