Identifying new blood markers for early detection of ovarian cancer recurrence

New Serum Biomarkers for Monitoring Early Diagnosis of Ovarian Cancer Recurrence Via Analysis of Immunoinflammation-related Protein Complexes in Blood

Observational Peking Union Medical College Hospital · NCT05410028

This study is trying to find new blood markers that can help detect if ovarian cancer comes back in women who have already been treated.

Quick facts

Study typeObservational
Enrollment1000 (estimated)
Ages20 Years to 70 Years
SexFemale
SponsorPeking Union Medical College Hospital Academic / other
Drugs / interventionschemotherapy
Locations1 site (Beijing, Beijing)
Trial IDNCT05410028 on ClinicalTrials.gov

What this trial studies

This observational study utilizes mass spectrometry to analyze immune inflammation-related protein complexes, glycopeptide omics, and tumor-related metabolomics in serum samples from patients with confirmed ovarian epithelial cancer. The study aims to identify potential metabolic small molecule biomarkers or marker profiles that could facilitate the early diagnosis of cancer recurrence. It will enroll at least 50 female patients at various stages of treatment and follow them until clinical relapse is confirmed.

Who should consider this trial

Good fit: Ideal candidates are females diagnosed with epithelial ovarian cancer who are 70 years old or younger.

Not a fit: Patients who are male, have other malignant tumors, or are non-compliant may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to earlier detection of ovarian cancer recurrence, improving patient outcomes.

How similar studies have performed: While this approach is innovative, similar studies have shown promise in identifying biomarkers for cancer recurrence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female
* A diagnosed patient with epithelial ovarian cancer
* Age ≤ 70

Exclusion Criteria:

* Male
* Suffering from other malignant tumors
* Non-compliant patient
* Age above 70

Where this trial is running

Beijing, Beijing

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ovarian Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.