Identifying Methylation Patterns in Head and Neck Cancer
Validation of Specific Methylation Profiles Ind Head and Neck Cancer - a Cohort Study
This study is trying to find unique chemical patterns in the blood of people with head and neck cancer to better understand the disease.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Aalborg University Hospital Academic / other |
| Locations | 1 site (Aalborg) |
| Trial ID | NCT04567056 on ClinicalTrials.gov |
What this trial studies
This observational study aims to define specific methylation profiles in patients diagnosed with head and neck squamous cell carcinoma (HNSCC). By analyzing blood samples, the researchers seek to identify unique methylation patterns associated with this type of cancer. The findings will be validated in a larger cohort to enhance the understanding of HNSCC and its molecular characteristics.
Who should consider this trial
Good fit: Ideal candidates include individuals with a confirmed diagnosis of head and neck squamous cell carcinoma who can provide informed consent.
Not a fit: Patients with other active cancers or uncontrolled comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for patients with head and neck squamous cell carcinoma.
How similar studies have performed: While similar studies have explored methylation patterns in various cancers, this specific focus on HNSCC is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Cancer group: Inclusion Criteria: * Written informed consent * Verified head and neck squamous cell carcinoma Exclusion Criteria: * Other active cancer * Uncontrolled comorbidity * Unable to give informed consent Control group: Inclusion Criteria: * Written informed consent * Normal ENT-examination Exclusion Criteria: * Other active cancer * Uncontrolled comorbidity * Unable to give informed consent
Where this trial is running
Aalborg
- Department of Otolaryngology - Head and Neck Surgery — Aalborg, Denmark (Recruiting)
Study contacts
- Principal investigator: Michael Gaihede, Professor — Department of Otolaryngology - Head and Neck Surgery, Aalborg University Hospital
- Study coordinator: Christian Danstrup, M.D.
- Email: csd@rn.dk
- Phone: +45 23800598
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.