Identifying heart issues in breast cancer patients using echocardiography
Official title: Technology Revising Ultrasound Solutions for Tomorrow - Anticancer-treatment Cardiotoxicity Identification by Echocardiography
Run by Norwegian University of Science and Technology · NCT06310330 · Data updated 2026-11-12
This study is testing if a simpler heart ultrasound can help find heart problems in breast cancer patients caused by their treatment, compared to a more detailed ultrasound.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | Norwegian University of Science and Technology Academic / other |
| Locations | 1 site (Trondheim) |
| Status | Recruiting |
| Started | March 8, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | August 13, 2026 |
| Trial ID | NCT06310330 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are breast cancer patients who are being referred for follow-up to assess potential cardiac dysfunction related to their cancer treatment.
✕Probably not a fit
Patients who are not willing or able to provide consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
TRUST-ACE aims to compare a simplified echocardiographic protocol that focuses on ventricular function against a comprehensive echocardiographic examination in breast cancer patients. The study will utilize a randomized design to assess the effectiveness of these approaches in identifying cancer treatment-related cardiac dysfunction (CTRCD). Additionally, it will evaluate novel tools for standardizing recordings and automating measurements like ejection fraction (EF) and global longitudinal strain (GLS) to enhance diagnostic precision in clinical practice.
Why it matters
Potential benefit: If successful, this study could lead to earlier detection and treatment of heart dysfunction in breast cancer patients, potentially preserving their cancer treatment options.
How similar studies have gone: Other studies have shown promise in using echocardiography for monitoring cardiac function in cancer patients, suggesting that this approach may be effective.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Breast cancer and referral for follow-up to identify potential CTRCD Exclusion Criteria: * Not willing or able to consent
Where it's running
-
St. Olavs hospital
Trondheim, Norway Recruiting
Study contacts
- Principal investigator: Espen Holte, MD, PhD — St. Olavs Hospital
- Study coordinator: Espen Holte, MD. PhD
- Email: espen.holte@stolav.no
- Phone: 92243119
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.