Identifying harmful IgA in IgA-related kidney disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The project enrolls adults with IgA nephropathy or IgA vasculitis and control patients undergoing renal biopsy to collect blood and tissue samples. Researchers will isolate and characterize IgA to examine glycosylation patterns, polymerization state, and anti-IgA autoantibodies. Molecular features of circulating IgA will be correlated with biopsy findings to identify forms with nephritogenic potential. Results aim to clarify mechanisms of IgA-driven glomerular injury and suggest biomarkers for recurrence risk after transplantation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients of interest: all patients with IgA nephropathy or rheumatoid purpura aged 18 years or older whose treatment requires a renal biopsy
* Control patients: all patients with a renal disease other than IgA nephropathy or rheumatoid purpura whose treatment requires a renal biopsy

Exclusion Criteria:

* Patient opposition
* Persons under legal guardianship
* Persons whose psychological health prevents the collection of non-opposition

Where it's running

• Chu Limoges
  Limoges, France Recruiting

Study contacts

• Study coordinator: Virginie PASCAL, Physician
• Email: virginie.pascal@chu-limoges.fr
• Phone: 05 55 08 71 11

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.