Identifying genetic risk factors for cardiomyopathy
Exome Sequencing Study in Cardiomyopathy to Identify New Risk Variants
Tongji Hospital · NCT03754101
This study is trying to find new genetic factors linked to cardiomyopathy by looking at the genes of patients with the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 4000 (estimated) |
| Sex | All |
| Sponsor | Tongji Hospital (other) |
| Locations | 1 site (Wuhan, Hubei) |
| Trial ID | NCT03754101 on ClinicalTrials.gov |
What this trial studies
This observational study aims to identify new genetic variants associated with cardiomyopathy by conducting whole exome sequencing on patients diagnosed with the condition. Patients were recruited from March 2003 to November 2017, and their genetic samples were compared with a paired control group. The study focuses on understanding the genetic basis of cardiomyopathy to improve prognosis and treatment options.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with cardiomyopathy as defined by the American Heart Association.
Not a fit: Patients with uncontrolled hypertension, significant valvular disease, or other specified exclusions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and management of cardiomyopathy through the identification of new genetic risk factors.
How similar studies have performed: Other studies have successfully identified genetic variants related to cardiomyopathy, suggesting that this approach has potential for meaningful discoveries.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: · Patients diagnosed as cardiomyopathy according to the definition of American Heart Association Exclusion Criteria: * Uncontrolled hypertension significant valvular disease * Mild ischemic heart disease * Significant systemic infection * Thyroid-induced cardiomyopathy * Excessive alcohol consumption * Precious cancer treatment including irradiation * Refusal to participate in the study
Where this trial is running
Wuhan, Hubei
- Tongji Hospital — Wuhan, Hubei, China (RECRUITING)
Study contacts
- Study coordinator: Chenze Li, MD candidate
- Email: lichenze@126.com
- Phone: 86-27-83663280
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Cardiomyopathy