Identifying genetic markers for radiation therapy response in breast cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify genetic and molecular biomarkers that predict how breast cancer patients respond to radiation therapy. It involves a monocentric approach at the Institute of Oncology Ljubljana, focusing on patients with ductal carcinoma in situ (DCIS) who are receiving adjuvant radiotherapy without systemic therapy. The study will assess adverse events related to radiation treatment over a five-year follow-up period and will analyze blood samples for biomarkers before, after, and during follow-up. Informed consent will be obtained from all participants, and the study has received ethical approval.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Breast cancer patients with DCIS with an indication for adjuvant radiation therapy

Exclusion Criteria:

* Any specific systemic oncological therapy

Where it's running

• Institute of Oncology Ljubljana
  Ljubljana, Slovenia Recruiting

Study contacts

• Principal investigator: Tanja Marinko, MD, PhD — Institute of Oncology Ljubljana
• Study coordinator: Tanja Marinko, MD, PhD
• Email: tmarinko@onko-i.si
• Phone: 0038615879505

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.