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Clinical trial Recruiting at 1 site Interventional Ages 50 and up

Identifying challenges to healthy aging in older adults with HIV

Official title: Identifying Challenges to Healthy Aging in Persons With HIV Age 50 and Older

Run by Wake Forest University Health Sciences · NCT05858034 · Data updated 2026-11-12

This study is trying to understand frailty in older adults with HIV and see if personalized activity and nutrition plans can help improve their health.

Quick facts

Study typeInterventional
Ages50 Years and up
SexAll
Enrollment100 (estimated)
SponsorWake Forest University Health Sciences
Academic / other
Locations1 site (Winston-Salem, North Carolina)
StatusRecruiting
StartedJune 27, 2023
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedAugust 27, 2026
Trial IDNCT05858034 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals aged 50 and older who are living with HIV and are followed by the Atrium Health Wake Forest Baptist Infectious Diseases Specialty Clinic.

Probably not a fit

Patients under the age of 50 or those unable to complete the required assessments may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to identify and characterize frailty and pre-frailty in individuals aged 50 and older living with HIV. It will utilize electronic medical record-based screening for frailty and comprehensive geriatric assessments, followed by offering customized activity and nutrition plans to some participants. Additionally, the study seeks to validate the electronic frailty index for predicting adverse outcomes and to correlate biomarkers of aging with symptoms of frailty. Participation in blood draws for research purposes is optional.

Why it matters

Potential benefit: If successful, this study could lead to improved health outcomes and quality of life for older adults living with HIV by addressing frailty.

How similar studies have gone: Other studies have shown success in addressing frailty in aging populations, but this specific approach targeting older adults with HIV is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Person living with human immunodeficiency virus (HIV)
* Age ≥50 years
* Followed by the Atrium Health Wake Forest Baptist Infectious Diseases Specialty Clinic (IDSC)
* Eligible for Ryan White Program
* Able to provide informed consent
* Pre-frail or frail by electronic frailty index (eFI)

Exclusion Criteria:

* Age \<50 years (study designed to characterize frailty in aging persons with HIV)
* Unable to complete the required assessments or questionnaires

Where it's running

  • Atrium Health Wake Forest Baptist
    Winston-Salem, North Carolina, United States     Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.