Identifying blood markers for early cancer detection

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The MEDECA study aims to improve early cancer diagnosis by identifying a multi-analyte blood test that can detect hidden cancers in patients with serious but nonspecific symptoms. It will involve 1500 patients referred to Danderyd Hospital's Diagnostic Center, where blood samples will be collected before a thorough cancer diagnostic work-up, including advanced imaging techniques. The study seeks to map occult cancer through biochemical analyses and collaboration with leading international scientists.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Age above 18 years

One or more of the following symptoms/clinical signs:

* General malaise
* Severe tiredness
* Unintentional weight loss
* Fever of unknown cause
* Uncharacteristic pain for \>4 weeks
* Abnormal laboratory tests (e.g., anemia, elevated alkaline phosphatase levels, erythrocyte sedimentation rate (ESR), calcium etc.)
* Diffuse pain without explanation
* Marked increase in drug usage
* Increasing health service seeking behavior
* Radiological findings suggestive of metastasis without known primary tumor or suspicion

Exclusion Criteria:

* Unwillingness to participate in the study
* Age below 18 years

Where it's running

• Danderyd Hospital
  Stockholm, Sweden Recruiting

Study contacts

• Principal investigator: Charlotte Thålin, M.D., Ph.D — Danderyd Hospital Karolinska Institutet
• Study coordinator: Charlotte Thålin, M.D., Ph.D.
• Email: charlotte.thalin@regionstockholm.se
• Phone: +46709565120

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.