Identifying Aortic Dissection in Patients with Chest Pain

Identification of Aortic Dissection Based on Pulse Oxygen and Ultrasound Doppler Waveforms

Observational Shanghai Zhongshan Hospital · NCT05699395

This study is trying to see if using special tests on the arms and legs can help doctors better identify aortic dissection in patients with chest pain.

Quick facts

Study typeObservational
Enrollment600 (estimated)
Ages18 Years to 90 Years
SexAll
SponsorShanghai Zhongshan Hospital Academic / other
Locations1 site (Shanghai)
Trial IDNCT05699395 on ClinicalTrials.gov

What this trial studies

This observational study focuses on patients presenting with high-risk chest pain who have been identified through computed tomography angiography (CTA) as having aortic dissection. The study aims to validate the effectiveness of using extremity oximetry and Doppler waveforms to accurately identify this condition. By establishing a cohort of these patients, researchers will analyze the correlation between the non-invasive methods and the diagnosis of aortic dissection. The findings could enhance diagnostic accuracy and improve patient outcomes.

Who should consider this trial

Good fit: Ideal candidates are individuals experiencing high-risk chest pain who have undergone CTA.

Not a fit: Patients in shock, coma, or with severe peripheral vascular diseases may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to quicker and more accurate identification of aortic dissection, potentially saving lives.

How similar studies have performed: While there have been studies on non-invasive methods for diagnosing aortic dissection, this specific approach using extremity oximetry and Doppler waveforms is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* High risk chest pain with CTA

Exclusion Criteria:

* shock
* coma
* severe peripheral vascular diseases

Where this trial is running

Shanghai

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aortic Dissection
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.