Identifying a biomarker for diabetic retinopathy
Biomarker of Diabetic Retinopathy
This study is trying to find a blood marker that can help show how healthy the eye blood vessels are in people with diabetic retinopathy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 192 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Indiana University Academic / other |
| Locations | 3 sites (Carmel, Indiana and 2 other locations) |
| Trial ID | NCT05079399 on ClinicalTrials.gov |
What this trial studies
This observational study aims to discover a biomarker that indicates the health status of retinal blood vessels in patients with diabetic retinopathy, a common complication of diabetes. By analyzing specialized cells in the blood, researchers hope to find a reliable marker that can provide insights into the condition of the retina. Participants will undergo blood draws to facilitate this analysis. The study focuses on individuals with established type 2 diabetes who meet specific eligibility criteria.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals with established type 2 diabetes who have not undergone certain eye treatments.
Not a fit: Patients with a history of malignancy, acute infections, or other specified eye conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and monitoring of diabetic retinopathy, enhancing patient care.
How similar studies have performed: While the approach of identifying biomarkers in diabetic retinopathy is being explored, this specific study's methodology is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Ability to cooperate with imaging procedures. * Health status: established type 2 diabetes * No history of panretinal photocoagulation (PRP) * No history of treatment with intravitreal agents for past 12 months Exclusion Criteria: * Previous or current malignancy * Acute or chronic infection (HIV, hepatitis B or C, tuberculosis) * Cerebral vascular accident or cerebral vascular procedure * Current pregnancy * History of organ transplantation * Presence of a graft (to avoid any effect of the graft) * History of previous vitrectomy * Subjects with a history of age-related macular degeneration age-related macular degeneration (AMD), glaucoma, uveitis, and branched or central vein occlusion.
Where this trial is running
Carmel, Indiana and 2 other locations
- Spring Mill Clinic — Carmel, Indiana, United States (Recruiting)
- Eskenazi Eye Clinic — Indianapolis, Indiana, United States (Recruiting)
- Glick Eye Institute — Indianapolis, Indiana, United States (Recruiting)
Study contacts
- Study coordinator: Ashay D Bhatwadekar, PhD, RPh
- Email: abhatwad@iupui.edu
- Phone: 3172785075
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.