ICU clinicians' early judgment of six-month recovery after out-of-hospital cardiac arrest
Official title: Validity of ICU Clinician's Appraisal of Proportionality in CPR
Run by University Hospital, Ghent · NCT07026773 · Data updated 2026-11-12
This project will test whether ICU doctors and nurses can, within the first 24 hours after admission, predict a patient's six-month brain recovery and quality of life after an out-of-hospital cardiac arrest.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | University Hospital, Ghent Academic / other |
| Locations | 9 sites (Innsbruck and 8 other locations) |
| Status | Recruiting |
| Started | May 18, 2025 |
| Main results expected | December 30, 2026 |
| Study ends | December 30, 2026 |
| Registry record updated | June 18, 2025 |
| Trial ID | NCT07026773 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Patients included are adults treated for out-of-hospital cardiac arrest who are enrolled in the international STEPCARE study and admitted to a participating ICU where their treating clinicians complete the questionnaire.
✕Probably not a fit
Patients who have in-hospital cardiac arrest, are not enrolled in STEPCARE, or whose outcomes are determined by immediate irreversible injuries are unlikely to benefit from this study's findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study asks ICU doctors and nurses who treat patients enrolled in the STEPCARE study to complete a brief questionnaire estimating six-month neurological outcome and quality of life based on clinical assessment during the first 24 hours after admission. Those clinician estimates will be compared to the actual neurological outcomes and patient-reported quality of life recorded by the STEPCARE study. The goal is to determine how well early bedside impressions match later, multimodal outcome data without changing patient care. No interventions are delivered as part of this study; it uses existing STEPCARE patients and clinician assessments at participating hospitals.
Why it matters
Potential benefit: If successful, earlier and more reliable clinician judgments could help align intensive care decisions with likely long-term outcomes, potentially reducing burdensome treatments and focusing resources on patients with better chances of meaningful recovery.
How similar studies have gone: Previous work on early clinician prognostication after cardiac arrest is limited and has produced mixed results, so this direct comparison with STEPCARE outcomes represents a relatively novel, pragmatic approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Doctors and nurses working in the Intensive Care Unit treating patients included in the STEPCARE study (NCT 05564754) Exclusion Criteria: * Doctors and nurses who do not have a direct treatment relationship with a patient included in the STEPCARE study
Where it's running
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Ziekenhuis Oost-Limburg
Genk, Belgium Recruiting -
Ghent University Hospital
Ghent, Belgium Recruiting -
Universitätsklinikum Lübeck
Lübeck, Germany Recruiting -
Policlinico San Martino
Genova, Italy Recruiting -
Wakefield Hospital
Wellington, New Zealand Recruiting -
King Abdulaziz Medical City
Riyadh, Saudi Arabia Recruiting
Show 3 more locations
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Medical University Innsbruck
Innsbruck, Austria Not yet recruiting -
Helsinki University Central Hospital
Helsinki, Finland Not yet recruiting -
Zürich University Hospital
Zurich, Switzerland Not yet recruiting
Study contacts
- Study coordinator: Patrick Druwé, MD, PhD
- Email: patrick.druwe@uzgent.be
- Phone: 003293321387
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.