I-HIT-MED registry for medulloblastoma, ependymoma, pineal and choroid plexus tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The I-HIT-MED registry prospectively enrolls children and adults diagnosed since 01.01.2012 with medulloblastoma, ependymoma, pineal tumours, or choroid plexus tumours who are not in a concurrent prospective therapeutic trial. It collects standardized clinical information, neuroradiology, pathology and molecular data and, where allowed, stores biological specimens such as tumour tissue, CSF, and blood. The registry aims to maintain and expand quality-assurance networks across participating national groups and to enable long-term follow-up including neuropsychological and patient-centered outcomes. Data and samples contributed by participating centers support development of standard treatment recommendations and collaborative biological research.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* all patients with above mentioned diagnosis of all ages (except for ependymoma WHO I°, pineal parenchymal tumour of intermediate differentiation and papillary tumour of the pineal region, who will be registered only if primary diagnosis was before the 18th birthday)
* any localisation of the primary tumour
* all clinical stages
* First diagnosis after 01.01.2012
* No inclusion into a prospective clinical trial for the same diagnosis, due to non-eligibility, national lack of trial approval, or individual refusal of participation.
* Written informed consent for data transfer and tumour sample submission according to the laws of each participating country is necessary.
* National and/ or local ethical committee approval according to the laws of each participating country is necessary.

Exclusion Criteria:

* Registration in another clinical trial for the same diagnosis (relapse is defined as a second diagnosis).
* Lack of valid ethical committee approval.

Where it's running

• University Hospital Aachen
  Aachen, Germany Recruiting
• Klinikum Augsburg
  Augsburg, Germany Recruiting
• Helios Klinikum Berlin-Buch
  Berlin, Germany Recruiting
• Charite Campus, University of Berlin
  Berlin, Germany Recruiting
• Evangelisches Krankenhaus Bielefeld
  Bielefeld, Germany Recruiting
• Klinikum Braunschweig
  Braunschweig, Germany Recruiting

+7 more sites. See ClinicalTrials.gov for the full list.

Study contacts

• Principal investigator: Stefan Rutkowski, Prof. — Universitätsklinikum Hamburg-Eppendorf
• Study coordinator: Stefan Rutkowski, Prof.
• Email: hitchem@uke.de
• Phone: +49-40-7410

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Blood biomarkers for treatment-related brain injury in children with brain tumors

  This project will test whether blood plasma biomarkers can show treatment-related brain injury in children with primary brain tumors by comparing those who receive radiotherapy, those who do not, and healthy children of the same age and sex.

  Recruiting Uppsala University · Uppsala · NCT07381959

• Targeted therapies for childhood and adolescent cancer

  This study is testing if new targeted treatments based on the genetic makeup of tumors can help kids and teens with cancer feel better and improve their chances of recovery.

  Recruiting at 12 sites Phase 1/2 Australian & New Zealand Children's Haematology/Oncology Group · Newcastle, New South Wales and 13 other locations · NCT06208657

• Precision medicine for children with cancer

  This study is testing if personalized medicine can improve treatment and outcomes for children with different types of cancer in Australia and New Zealand.

  Recruiting at 10 sites Australian & New Zealand Children's Haematology/Oncology Group · Adelaide and 10 other locations · NCT05504772

• Understanding cognitive function in children with brain tumors

  This study looks at how brain tumors affect thinking skills in children aged 4-18 to help understand their cognitive challenges better.

  Recruiting Washington University School of Medicine · St Louis, Missouri · NCT02914067

• Testing drug sensitivity and genetic profiling for pediatric cancer patients

  This study is testing a new way to find the best cancer treatments for children by looking at how their tumor cells respond to different drugs and comparing those results to standard treatments.

  Recruiting Phase 1 Florida International University · Miami, Florida · NCT05857969

• Long-term effects of childhood solid tumors and their treatments in survivors

  This study looks at the long-term health and quality of life of childhood cancer survivors treated for solid tumors in France to see how their past treatments affect them now.

  Recruiting at 5 sites Institut National de la Santé Et de la Recherche Médicale, France · Amiens and 35 other locations · NCT01620372

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.