Hypnosis to improve attention and reduce fatigue in stroke, TBI, and MS
Official title: Hypnosis and Attention in Patients With a Neurological Disease
Run by Luzerner Kantonsspital · NCT07256704 · Data updated 2026-11-12
This trial tests whether adding hypnosis to standard rehab can help adults with stroke, traumatic brain injury, or multiple sclerosis improve attention and feel less fatigued.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 48 (estimated) |
| Sponsor | Luzerner Kantonsspital Academic / other |
| Locations | 1 site (Lucerne) |
| Status | Recruiting |
| Started | November 18, 2025 |
| Main results expected | July 31, 2029 |
| Study ends | July 31, 2029 |
| Registry record updated | August 14, 2026 |
| Trial ID | NCT07256704 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with a clinical diagnosis of stroke, TBI, or MS who are treated as inpatients or outpatients at the Clinic for Neurology and Neurorehabilitation, speak German, can consent, and do not have active psychiatric illness or EEG‑interfering implants are ideal candidates.
✕Probably not a fit
People with active psychiatric disorders, implanted neurostimulation devices or cochlear implants, scalp conditions that prevent EEG electrode placement, or who cannot follow German instructions may not benefit from or be eligible for this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults with stroke, traumatic brain injury, or multiple sclerosis often have attention problems and reduced spontaneous visual exploration that limit daily function. This feasibility study integrates hypnosis sessions with participants' usual neurorehabilitation care and includes sham-hypnosis sessions while recording EEG to track brain activity during interventions. The team will measure feasibility and acceptability and look for preliminary changes in attention, free visual exploration, and fatigue using behavioral tests and EEG markers. Participants are German-speaking inpatients or outpatients at the Clinic for Neurology and Neurorehabilitation at Luzerner Kantonsspital who are 18 years or older and able to give informed consent.
Why it matters
Potential benefit: If successful, adding hypnosis could improve attention and reduce fatigue, helping people regain more independence in daily activities.
How similar studies have gone: Hypnosis has shown benefits in pain and fatigue in other medical settings, but its application to attention and visual exploration in stroke, TBI, and MS is relatively novel with limited prior evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ICD-10 Diagnosis of stroke, TBI or MS * Admitted to the inpatient and/or outpatient in the Clinic for Neurology and Neurorehabilitation * Age 18 years old or older * Understanding the German language * Written informed consent Exclusion Criteria: \- Psychiatric disease Exclusion criteria for the EEG: \- Scalp or skin conditions that interfere with EEG electrode placement (e.g. open wounds, infections, severe psoriasis) Implanted medical or neurostimulation devices that interfere with EEG electrode placement (e.g. deep brain stimulators, cochlear implants)
Where it's running
-
Luzerner Kantonsspital
Lucerne, Switzerland Recruiting
Study contacts
- Study coordinator: Thomas Nyffeler, Prof. Dr. med.
- Email: thomas.nyffeler@luks.ch
- Phone: +41412055686
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.